(19)

(11)

EP 4 823 680 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24820775.5 (22) Date of filing: 11.12.2024

(51) International Patent Classification (IPC):  A61P 35/00(2006.01) C07D 487/04(2006.01) A61K 31/4985(2006.01) (52) Cooperative Patent Classification (CPC): C07D 487/04; A61K 31/4985; A61P 35/00 (86) International application number: PCT/EP2024/085803 (87) International publication number: WO 2025/125383 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 11.12.2023 EP 23215619 08.08.2024 EP 24193618 (71) Applicant: Synthon B.V. 6545 CM Nijmegen (NL)	(72) Inventors: DYMACEK, Bohumil 67817 Blansko (CZ) HEGEDUS, Michal 67817 Blansko (CZ) (74) Representative: Dobsík, Martin  Synthon B.V. Microweg 22 6545 CM Nijmegen 6545 CM Nijmegen (NL)