(19)
(11) EP 4 823 682 A1

(12)

(43) Date of publication:
21.10.2026 Bulletin 2026/43

(21) Application number: 24828044.8

(22) Date of filing: 12.12.2024
(51) International Patent Classification (IPC): 
A61P 35/00(2006.01)
C07K 16/28(2006.01)
 C07K 16/00(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 2039/505; C07K 2317/92; C07K 2317/50; C07K 2317/24; C07K 2317/33; C07K 16/2809; C07K 16/28; A61P 35/00; C07K 2317/565; C07K 2317/30; C07K 16/005
(86) International application number:
PCT/EP2024/085813
(87) International publication number:
WO 2025/125386 (19.06.2025 Gazette 2025/25)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 14.12.2023 EP 23216593

(71) Applicant: F. Hoffmann-La Roche AG
4070 Basel (CH)

(72) Inventors:
  • BORIN, Nicole
    8952 Schlieren (CH)
  • DEHÒ, Lorenzo
    8952 Schlieren (CH)
  • GASSNER, Christian Robert
    82377 Penzberg (DE)
  • GUERIPEL, Xavier
    8952 Schlieren (CH)
  • HUGENMATTER, Adrian
    8952 Schlieren (CH)
  • KLEIN, Christian
    8952 Schlieren (CH)
  • LA SALA, Grégory
    8952 Schlieren (CH)
  • LECLAIR, Stéphane Gérard Alain
    82377 Penzberg (DE)
  • MENDE, Fanny
    8952 Schlieren (CH)
  • MENIETTI, Elena
    8952 Schlieren (CH)
  • MOESSNER, Ekkehard
    8952 Schlieren (CH)
  • PINCHA, Mudita
    8952 Schlieren (CH)
  • UMAÑA FERNÁNDEZ, Pablo
    8952 Schlieren (CH)

(74) Representative: Müller-Afraz, Simona 
F. Hoffmann-La Roche AG Patent Department Grenzacherstrasse 124
4070 Basel
4070 Basel (CH)

   


(54) ANTIBODIES THAT BIND TO FOLR1 AND METHODS OF USE