(19)
(11) EP 4 823 684 A1

(12)

(43) Date of publication:
21.10.2026 Bulletin 2026/43

(21) Application number: 24834546.4

(22) Date of filing: 13.12.2024
(51) International Patent Classification (IPC): 
A61P 35/00(2006.01)
C07D 213/75(2006.01)
C07D 413/14(2006.01)
A61K 31/4427(2006.01)
C07D 407/14(2006.01)
C07D 471/04(2006.01)
(52) Cooperative Patent Classification (CPC):
A61P 35/00; C07D 213/75; C07D 471/04; C07D 407/14; C07D 413/14; A61K 45/06
(86) International application number:
PCT/US2024/060064
(87) International publication number:
WO 2025/129019 (19.06.2025 Gazette 2025/25)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 13.12.2023 US 202363609562 P
19.01.2024 US 202463622680 P

(71) Applicant: Deciphera Pharmaceuticals, LLC
Waltham, MA 02451 (US)

(72) Inventors:
  • STUEVEN, Kristen L.
    Waltham, Massachusetts 02451 (US)
  • ZWICKER, Jeffery
    Waltham, Massachusetts 02451 (US)
  • AHN, Yu Mi
    Waltham, Massachusetts 02451 (US)
  • FLYNN, Daniel L.
    Waltham, Massachusetts 02451 (US)

(74) Representative: Marks & Clerk LLP 
15 Fetter Lane
London EC4A 1BW
London EC4A 1BW (GB)

   


(54) VPS34 INHIBITORS AND METHODS OF USE THEREOF