(19)

(11)

EP 4 824 018 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24904738.2 (22) Date of filing: 10.12.2024

(51) International Patent Classification (IPC):  C07C 13/263(2006.01) A61K 31/16(2006.01) C07C 235/40(2006.01) (52) Cooperative Patent Classification (CPC): C07C 323/12; C07C 2601/18; A61K 47/64 (86) International application number: PCT/US2024/059402 (87) International publication number: WO 2025/128586 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 11.12.2023 US 202363608771 P (71) Applicant: The Regents of the University of California Oakland, CA 94607 (US)	(72) Inventors: WILSON, Ross C. Berkeley, California 94708 (US) MURTHY, Niren El Cerrito, California 94530 (US) ZHAO, Sheng El Cerrito, California 94530 (US) SHARMA, Rohit Kumar Berkeley, California 94702 (US) BAEHR, Christopher Berkeley, California 94704 (US) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)