(19)
(11) EP 4 824 036 A1

(12)

(43) Date of publication:
21.10.2026 Bulletin 2026/43

(21) Application number: 24834955.7

(22) Date of filing: 12.12.2024
(51) International Patent Classification (IPC): 
C07C 233/36(2006.01)
A61K 9/127(2025.01)
(52) Cooperative Patent Classification (CPC):
C07C 233/36; A61K 9/1271; A61K 9/5123
(86) International application number:
PCT/US2024/059895
(87) International publication number:
WO 2025/128902 (19.06.2025 Gazette 2025/25)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 13.12.2023 US 202363609852 P

(71) Applicant: Tidal Therapeutics, Inc.
Cambridge, MA 02139 (US)

(72) Inventors:
  • ALI, Mir
    Cambridge, Massachusetts 02141 (US)
  • RICHARDS, Jennifer
    Cambridge, MA 02141 (US)
  • SAWYER, Andrew
    Cambridge, MA 02141 (US)

(74) Representative: Zwicker, Jörk 
Zwicker Schnappauf & Partner Patentanwälte PartG mbB Hansastraße 32
80686 München
80686 München (DE)

   


(54) IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES, AND METHODS OF SYNTHESIS AND USE THEREOF