(19)
(11) EP 4 824 040 A1

(12)

(43) Date of publication:
21.10.2026 Bulletin 2026/43

(21) Application number: 23829015.9

(22) Date of filing: 12.12.2023
(51) International Patent Classification (IPC): 
C07D 207/48(2006.01)
C07D 405/12(2006.01)
C07D 413/12(2006.01)
A61P 1/00(2006.01)
A61K 31/4025(2006.01)
 C07D 277/64(2006.01)
C07D 409/12(2006.01)
C07D 417/12(2006.01)
A61P 25/00(2006.01)
(52) Cooperative Patent Classification (CPC):
C07D 417/12; C07D 409/12; C07D 207/48; C07D 277/64; C07D 413/12; C07D 405/12; A61P 25/00; A61P 1/00
(86) International application number:
PCT/EP2023/085388
(87) International publication number:
WO 2025/124698 (19.06.2025 Gazette 2025/25)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(71) Applicant: Idorsia Pharmaceuticals Ltd
4123 Allschwil (CH)

(72) Inventors:
  • AISSAOUI, Hamed
    4123 Allschwil (CH)
  • BEZENCON, Olivier
    4123 Allschwil (CH)
  • HEIDMANN, Bibia
    4123 Allschwil (CH)
  • MUEHLEMANN, Andreas
    4123 Allschwil (CH)
  • POZZI, Davide
    4123 Allschwil (CH)
  • RICHARD-BILDSTEIN, Sylvia
    4123 Allschwil (CH)
  • SIEGRIST, Romain
    4123 Allschwil (CH)

(74) Representative: Kamdzhilov, Yavor 
Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91
4123 Allschwil
4123 Allschwil (CH)

   


(54) ARYL SULFONE AND SULFANONE DERIVATIVES AS OREXIN RECEPTOR MODULATORS