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(11)

EP 4 824 046 A1

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(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24904977.6 (22) Date of filing: 13.12.2024

(51) International Patent Classification (IPC):  C07D 241/04(2006.01) A61P 13/12(2006.01) C07D 233/64(2006.01) C07D 265/30(2006.01) C07D 207/16(2006.01) (52) Cooperative Patent Classification (CPC): C07D 233/64; A61P 13/12; C07D 207/16; C07D 295/185; C07C 233/56; C07C 323/59 (86) International application number: PCT/US2024/060075 (87) International publication number: WO 2025/129026 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 15.12.2023 US 202363610507 P (71) Applicant: Rutgers, the State University of New Jersey New Brunswick, NJ 08901 (US)	(72) Inventors: HU, Longqin Belle Mead, New Jersey 08502 (US) WANG, Yiling Shanghai, Zhejiang 201702 (CN) (74) Representative: Hoffmann Eitle  Patent- und Rechtsanwälte PartmbB Arabellastraße 30 81925 München 81925 München (DE)