(19)

(11)

EP 4 824 050 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24834945.8 (22) Date of filing: 10.12.2024

(51) International Patent Classification (IPC):  C07D 401/14(2006.01) A61P 3/10(2006.01) A61K 31/506(2006.01) (52) Cooperative Patent Classification (CPC): C07D 401/14; A61P 3/10 (86) International application number: PCT/US2024/059368 (87) International publication number: WO 2025/128561 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 11.12.2023 WO PCT/CN2023/137919 (71) Applicant: Carmot Therapeutics Inc. South San Francisco, California 94080 (US)	(72) Inventors: WANG, Xiaoyang Shanghai 200131 (CN) MA, Xiaoyu Shanghai 200131 (CN) ROBIN, Jennifer 4303 Kaiseraugst (CH) DE PAUL, Susan Margaret 4303 Kaiseraugst (CH) LAI, Felix Shang Chung Berkeley, CA 94710 (US) (74) Representative: Vitra, Hermeto  F. Hoffmann-La Roche AG Patent Department Grenzacherstrasse 124 4070 Basel 4070 Basel (CH)