(19)

(11)

EP 4 824 054 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24904974.3 (22) Date of filing: 13.12.2024

(51) International Patent Classification (IPC):  C07D 403/12(2006.01) A61P 11/00(2006.01) C07D 215/48(2006.01) C07D 263/58(2006.01) C07D 401/12(2006.01) C07D 405/04(2006.01) C07D 413/04(2006.01) C07D 417/12(2006.01) A61P 1/16(2006.01) C07D 209/42(2006.01) C07D 235/24(2006.01) C07D 277/68(2006.01) C07D 403/04(2006.01) C07D 405/12(2006.01) C07D 413/12(2006.01) C07D 471/04(2006.01) (52) Cooperative Patent Classification (CPC): C07D 417/12; C07D 405/12; C07D 209/42; C07D 403/12; C07D 401/12; C07D 471/04; C07D 401/06; C07D 403/06; C07D 413/06; C07D 403/04; C07D 405/04; C07D 413/04; C07D 277/68; C07D 263/58; C07D 235/24; C07D 307/84; C07D 413/12; C07D 215/48; C07D 491/048; C07D 491/052; C07D 513/04; C07D 409/12; A61P 11/00 (86) International application number: PCT/US2024/060071 (87) International publication number: WO 2025/129023 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 15.12.2023 US 202363610803 P (71) Applicant: Rectify Pharmaceuticals, Inc. Cambridge, Massachusetts 02139 (US)	(72) Inventors: FULLER, Nathan Oliver Arlington, Massachusetts 02474 (US) HUGHES, Robert Owen Newtown, Connecticut 06470 (US) BEMIS, Guy San Diego, California 92109 (US) BOSANAC, Todd Burlington, Connecticut 06013 (US) NG, Pui Yee Lexington, Massachusetts 02420 (US) (74) Representative: Graham Watt & Co  Fulwood House 12 Fulwood Place London WC1V 6HR London WC1V 6HR (GB)