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EP 4 824 063 A1

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(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24904915.6 (22) Date of filing: 12.12.2024

(51) International Patent Classification (IPC):  C07D 487/00(2006.01) A61K 31/44(2006.01) A61K 31/498(2006.01) C07D 213/72(2006.01) A61K 31/4162(2006.01) A61K 31/497(2006.01) C07C 209/60(2006.01) C07D 241/04(2006.01) (52) Cooperative Patent Classification (CPC): C07D 487/04 (86) International application number: PCT/US2024/059896 (87) International publication number: WO 2025/128903 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 13.12.2023 US 202363609795 P (71) Applicant: Eikon Therapeutics Inc. Millbrae, CA 94030 (US)	(72) Inventors: WANG, Silas Millbrae, CA 94030 (US) BECK, Hilary Millbrae, CA 94030 (US) RAMOS, Angel Millbrae, CA 94030 (US) (74) Representative: Snaith, James Michael et al Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL London WC1X 8NL (GB)