(19)

(11)

EP 4 824 068 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24905030.3 (22) Date of filing: 13.12.2024

(51) International Patent Classification (IPC):  C07D 491/18(2006.01) A61P 25/36(2006.01) A61P 25/32(2006.01) C07D 471/18(2006.01) (52) Cooperative Patent Classification (CPC): C07D 471/22; C07D 491/048; C07D 491/22; A61K 31/439; C07D 471/08; A61K 31/55 (86) International application number: PCT/US2024/060205 (87) International publication number: WO 2025/129121 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 14.12.2023 US 202363610295 P (71) Applicant: ATAI Therapeutics, Inc. New York, NY 10119 (US)

(72) Inventors: KHAN, Tanweer A. New York, New York 10119 (US) SHORT, Glenn New York, New York 10119 (US) PERNI, Robert B. New York, New York 10119 (US) GIBBS, Alan C. New York, New York 10119 (US) O'MEARA, Jeffrey New York, New York 10119 (US) KAUR, Harpreet New York, New York 10119 (US) ALI, Ahmed Magdy New York, New York 10119 (US) (74) Representative: Smart, Jessica Ann et al Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL London WC1X 8NL (GB)