(19)
(11) EP 4 824 071 A1

(12)

(43) Date of publication:
21.10.2026 Bulletin 2026/43

(21) Application number: 24821920.6

(22) Date of filing: 11.12.2024
(51) International Patent Classification (IPC): 
C07D 495/04(2006.01)
A61P 11/00(2006.01)
 A61K 31/407(2006.01)
(52) Cooperative Patent Classification (CPC):
C07D 495/04; A61P 11/00
(86) International application number:
PCT/EP2024/085613
(87) International publication number:
WO 2025/125295 (19.06.2025 Gazette 2025/25)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 13.12.2023 EP 23216183

(71) Applicant: Chiesi Farmaceutici S.p.A.
43122 Parma (IT)

(72) Inventors:
  • BRUNO, Paolo
    43122 Parma (IT)
  • PALA, Daniele
    43122 Parma (IT)
  • CUZZOLIN, Alberto
    43122 Parma (IT)

(74) Representative: Chiesi Farmaceutici S.p.A. 
Via Palermo, 26/A
43122 Parma
43122 Parma (IT)

   


(54) THIENO-INDOLE AMIDE DERIVATIVES AS PHGDH INHIBITORS