(19)

(11)

EP 4 824 080 A2

(12)

(88) Date of publication A3: 31.07.2025 (43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24837746.7 (22) Date of filing: 11.12.2024

(51) International Patent Classification (IPC):  C07K 14/575(2006.01) A61P 3/10(2006.01) A61K 47/00(2006.01) A61P 1/00(2006.01) A61K 38/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 38/00; C07K 14/575; A61P 1/00; A61P 3/10 (86) International application number: PCT/US2024/059456 (87) International publication number: WO 2025/128624 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 12.12.2023 US 202363609336 P 12.12.2023 US 202363609340 P (71) Applicant: Carmot Therapeutics Inc. South San Francisco, California 94080 (US)	(72) Inventors: HERGARDEN, Anne Christina San Francisco, CA 94080 (US) KRISHNAN, Shyam San Francisco, CA 94080 (US) LEE, Craig San Francisco, CA 94080 (US) MOYA IV, Enrique Miguel Stanford, CA 94305 (US) TANG, Yu Ching San Francisco, CA 94080 (US) (74) Representative: Bernard, Guillaume  F. Hoffmann-La Roche AG Patent Department Grenzacherstrasse 124 4070 Basel 4070 Basel (CH)