(19)

(11)

EP 4 824 091 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24821059.3 (22) Date of filing: 09.12.2024

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) A61P 37/00(2006.01) A61P 35/00(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/30; C07K 16/32; C07K 16/2866; C07K 16/28; C07K 2317/72; C07K 2317/71; C07K 2317/35; C07K 2317/524; C07K 2317/526; C07K 2317/732; C07K 16/4283; C07K 2319/50; A61P 35/00; A61P 37/00; C07K 2317/34; C07K 2317/70; C07K 2319/00 (86) International application number: PCT/EP2024/085184 (87) International publication number: WO 2025/125118 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 11.12.2023 EP 23215429 (71) Applicant: F. Hoffmann-La Roche AG 4070 Basel (CH)	(72) Inventors: AMANN, Maria 8952 Schlieren (CH) KARAKOÇ HUTTER, Idil 8952 Schlieren (CH) KLEIN, Christian 8952 Schlieren (CH) SURÓWKA, Marlena Katarzyna 8952 Schlieren (CH) (74) Representative: Buser, Andres  F. Hoffmann-La Roche AG Patent Department Grenzacherstrasse 124 4070 Basel 4070 Basel (CH)