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(11)

EP 4 824 098 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24841336.1 (22) Date of filing: 12.12.2024

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) A61K 39/395(2006.01) A61P 37/06(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/2803; A61P 37/06; C07K 2317/33; C07K 2317/75; C07K 2317/92; C07K 2317/34 (86) International application number: PCT/US2024/059792 (87) International publication number: WO 2025/128836 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 13.12.2023 US 202363609523 P (71) Applicant: Eli Lilly and Company Indianapolis, IN 46285 (US)

(72) Inventors: BALASUBRAMANIAM, Deepa Indianapolis, Indiana 46206-6288 (US) LIN, Yaqiong Indianapolis, Indiana 46206-6288 (US) MUENCH, David Indianapolis, Indiana 46206-6288 (US) NA, Songqing Indianapolis, Indiana 46206-6288 (US) WITEK, Marta Antonina Indianapolis, Indiana 46206-6288 (US) XU, Jianghuai Indianapolis, Indiana 46206-6288 (US) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)