(19)

(11)

EP 4 824 105 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24905039.4 (22) Date of filing: 13.12.2024

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) C07K 16/00(2006.01) C07K 16/46(2006.01) A61K 39/00(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/2818; C07K 16/2866; C07K 2317/31; C07K 2317/55; C07K 2317/21; C07K 2317/92; C07K 2317/76; C07K 2317/41; C07K 2317/73; C07K 2317/94 (86) International application number: PCT/US2024/060225 (87) International publication number: WO 2025/129132 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 14.12.2023 US 202363610366 P 08.02.2024 US 202463551508 P (71) Applicant: Invenra Inc. Madison, WI 53719 (US)	(72) Inventors: GOLDUFSKY, Josef, W. Madison, WI 53719 (US) HAMMER, Bonnie Madison, WI 53719 (US) PULUKKUNAT, Dileep, Kumar Madison, WI 53719 (US) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)