(19)

(11)

EP 4 824 237 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24840911.2 (22) Date of filing: 12.12.2024

(51) International Patent Classification (IPC):  C12N 5/0789(2010.01) (52) Cooperative Patent Classification (CPC): C12N 5/0647; C12N 2501/125; C12N 2501/145; C12N 2501/26; C12N 2501/22; C12N 2501/2306; C12N 2501/23; C12N 2501/155; C12N 2506/00; C12N 2506/11 (86) International application number: PCT/IL2024/051174 (87) International publication number: WO 2025/126208 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 12.12.2023 US 202363608838 P (71) Applicant: Accellta Ltd. 3200004 Haifa (IL)	(72) Inventors: AMIT, Michal 2014200 Yuvalim (IL) DOMEV COHEN, Hagit 2623198 Kiryat-Motzkin (IL) (74) Representative: Boult Wade Tennant LLP  Salisbury Square House 8 Salisbury Square London EC4Y 8AP London EC4Y 8AP (GB)