COMPOSITIONS AND METHODS FOR ALLELE-SPECIFIC MYH7 GENE EDITING

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EP 4 824 239 A1

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(43)	Date of publication:
	21.10.2026 Bulletin 2026/43

(21)	Application number: 24905013.9

(22)	Date of filing: 13.12.2024

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International Patent Classification (IPC):

C12N 5/10^(2006.01)
C12N 15/11^(2006.01)
A61P 9/10^(2006.01)
C12N 15/90^(2006.01)
A61K 48/00^(2006.01)

C12N 9/22^(2006.01)
C12N 15/113^(2010.01)
C07K 14/47^(2006.01)
C12N 5/00^(2006.01)
C12N 15/86^(2006.01)

(52)	Cooperative Patent Classification (CPC):
	A61P 9/10; C12N 15/113; C12N 15/90; C12N 2750/14143; A61K 48/005; C12N 9/226; C12N 2310/20; C12N 2320/34; C12N 5/0657; C12N 2501/33; C12N 2501/415; C12N 2510/00; C12N 2506/45

(86)	International application number:
	PCT/US2024/060165

(87)	International publication number:
	WO 2025/129095 (19.06.2025 Gazette 2025/25)

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
	Designated Extension States:
	BA
	Designated Validation States:
	GE KH MA MD TN

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Priority:

14.12.2023 US 202363610306 P

(71)	Applicant: Tenaya Therapeutics, Inc.
	South San Francisco, CA 94080 (US)

(72)	Inventors:
	PRIEST, James Rush South San Francisco, California 94080 (US) HOEY, Timothy C. South San Francisco, California 94080 (US)

(74)	Representative: Goodwin Procter (UK) LLP
	Sancroft, 10-15 Newgate Street EC1A 7AZ / London EC1A 7AZ / London (GB)

(54)	COMPOSITIONS AND METHODS FOR ALLELE-SPECIFIC MYH7 GENE EDITING