HIGH PRODUCTION OF RECOMBINANT PROTEIN BY MAKING CELL HYBRIDS AND ENRICHING FOR A PREFERRED MITOCHONDRIAL PHENOTYPE - Patent 4824240

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EP 4 824 240 A1

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(43)	Date of publication:
	21.10.2026 Bulletin 2026/43

(21)	Application number: 23844448.3

(22)	Date of filing: 13.12.2023

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International Patent Classification (IPC):

C12N 5/12^(2006.01)

(52)	Cooperative Patent Classification (CPC):
	C12N 2510/02; C07K 2317/14; C12N 5/16; C12N 5/12; C07K 16/32

(86)	International application number:
	PCT/US2023/083811

(87)	International publication number:
	WO 2025/128096 (19.06.2025 Gazette 2025/25)

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
	Designated Extension States:
	BA
	Designated Validation States:
	KH MA MD TN

(71)	Applicant: CHO Plus Inc.
	South San Francisco, California 94080 (US)

(72)	Inventors:
	FORMAN, Lawrence South San Francisco, California 94080 (US) NGO, Kathy South San Francisco, California 94080 (US)

(74)	Representative: Bassil, Nicholas Charles et al
	Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL London WC1X 8NL (GB)

(54)	HIGH PRODUCTION OF RECOMBINANT PROTEIN BY MAKING CELL HYBRIDS AND ENRICHING FOR A PREFERRED MITOCHONDRIAL PHENOTYPE