(19)

(11)

EP 4 824 246 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24829108.0 (22) Date of filing: 13.12.2024

(51) International Patent Classification (IPC):  C12N 15/10(2006.01) C40B 40/08(2006.01) C12N 9/00(2006.01) (52) Cooperative Patent Classification (CPC): C07K 2319/95; C07K 2319/70; C07K 2319/30; C40B 40/08; C12N 15/1034; C12N 9/93 (86) International application number: PCT/EP2024/086358 (87) International publication number: WO 2025/125630 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 15.12.2023 EP 23216980 (71) Applicant: MedImmune Limited Cambridge CB2 0AA (GB)	(72) Inventors: HUNT, James Cambridge Cambridgeshire CB2 0AA (GB) FLETCHER, Alice Cambridge Cambridgeshire CB2 0AA (GB) GILBERTO, Samuel Cambridge Cambridgeshire CB2 0AA (GB) (74) Representative: AstraZeneca Intellectual Property  Eastbrook House Shaftesbury Road Cambridge CB2 8BF Cambridge CB2 8BF (GB)