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(11)

EP 4 824 260 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24904870.3 (22) Date of filing: 12.12.2024

(51) International Patent Classification (IPC):  C12N 15/113(2010.01) A61K 48/00(2006.01) A61K 31/7088(2006.01) A61P 25/00(2006.01) (52) Cooperative Patent Classification (CPC): A61P 25/00; C12N 2310/315; C12N 2310/3341; C12N 15/1137; C12N 2310/11; C12N 2310/341; A61K 31/7125; A61K 31/712   C-Sets: C12N 2310/321, C12N 2310/3525; (86) International application number: PCT/US2024/059763 (87) International publication number: WO 2025/128816 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 13.12.2023 US 202363609703 P (71) Applicant: Kicho Inc. New York, NY 10016 (US)	(72) Inventors: QUIGLEY, Oliver S. C. New York, New York 10016 (US) PERLSTEIN, Ethan New York, New York 10016 (US) (74) Representative: Mathys & Squire  32 London Bridge Street The Shard London SE1 9SG London SE1 9SG (GB)