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EP 4 824 263 A1

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(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24904949.5 (22) Date of filing: 13.12.2024

(51) International Patent Classification (IPC):  C12N 15/113(2010.01) A01H 1/00(2006.01) A01P 7/04(2006.01) C12N 15/82(2006.01) A01N 57/10(2006.01) (52) Cooperative Patent Classification (CPC): Y02A 40/146; A01P 7/04; C12N 2310/14; C12N 15/1138; A01N 57/16; C12N 15/8286 (86) International application number: PCT/US2024/059991 (87) International publication number: WO 2025/128967 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 15.12.2023 US 202363610693 P 07.11.2024 US 202463717613 P (71) Applicants: Iowa State University Research Foundation, Inc. Ames, IA 50010 (US) The United States of America, as Represented by the Secretary of Agriculture Washington, DC 20250 (US)

(72) Inventors: O'NEAL, Matthew Ames, Iowa 50011 (US) VALMORBIDA, Ivair Ames, Iowa 50011 (US) COATES, Brad Ames, Iowa 50011 (US) ARNEMANN, Jonas Ames, Iowa 50011 (US) (74) Representative: Bradbury, Simon Timothy Nicholas  Withers & Rogers LLP 2 London Bridge London SE1 9RA London SE1 9RA (GB)