(19)

(11)

EP 4 824 265 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24901871.4 (22) Date of filing: 13.12.2024

(51) International Patent Classification (IPC):  C12N 15/62(2006.01) A61K 47/54(2017.01) C07J 5/00(2006.01) C07K 19/00(2006.01) C12N 15/85(2006.01) A61K 39/00(2006.01) A61P 37/06(2006.01) C07K 14/47(2006.01) C12N 15/12(2006.01) C12N 15/87(2006.01) (52) Cooperative Patent Classification (CPC): A61P 37/06; C07K 14/47; C12N 15/88; A61K 48/0008; C07J 5/0076; C07K 2319/02; C07K 2319/50; C07K 2319/06; C07K 14/62; C12N 9/88; A61K 47/6929; A61K 47/543; A61K 2039/55555; A61K 39/0005; A61K 2039/53; A61K 39/0008; A61K 2039/54; A61K 2039/545; A61K 39/39; A61K 2039/55566 (86) International application number: PCT/CA2024/051664 (87) International publication number: WO 2025/123147 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 14.12.2023 US 202363609977 P 14.12.2023 US 202363609983 P (71) Applicant: Integrated Nanotherapeutics Inc. Burnaby BC V5G 4X4 (CA)	(72) Inventors: TAM, Yuen Yi Burnaby, British Columbia V5G 4X4 (CA) CHEN, Sam Burnaby, British Columbia V5G 4X4 (CA) DENROCHE, Heather Burnaby, British Columbia V5G 4X4 (CA) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)