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EP 4 824 269 A1

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(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24904954.5 (22) Date of filing: 13.12.2024

(51) International Patent Classification (IPC):  C12N 15/82(2006.01) C12N 15/52(2006.01) A01N 63/60(2020.01) C12N 15/113(2010.01) A01H 5/10(2018.01) (52) Cooperative Patent Classification (CPC): C12N 15/1137; C12N 2310/14; C12N 15/52; C12N 2310/531; A01P 7/04; A01N 63/60   C-Sets: A01N 63/60, A01N 25/006; (86) International application number: PCT/US2024/060004 (87) International publication number: WO 2025/128977 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 14.12.2023 US 202363610376 P (71) Applicants: Natural Resources Institute Chatham Maritime ME4 4TB (GB) Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. 9139002 Jerusalem (IL) Donald Danforth Plant Science Center St. Louis, MO 63132 (US) National Agricultural Research Organization Entebbe (UG)

(72) Inventors: COLVIN, John Chatham Maritime ME4 4TB (GB) VAN BRUNSCHOT, Sharon, L. Chatham Maritime ME4 4TB (GB) SWAMY, Rekha Chatham Maritime ME4 4TB (GB) SEAL, Susan Chatham Maritime ME4 4TB (GB) MORIN, Shai 9139002 Givat-Ram, Jerusalem (IL) MALKA, Osnat 9139002 Givat-Ram, Jerusalem (IL) WINTRAUBE, Dor 9139002 Givat-Ram, Jerusalem (IL) TAYLOR, Nigel St. Louis, MO 63132 (US) NARAYANAN, Narayanan St. Louis, MO 63132 (US) ALICAI, Titus Entebbe (UG) KAWEESI, Tadeo Entebbe (UG) (74) Representative: V.O.  P.O. Box 87930 2508 DH Den Haag 2508 DH Den Haag (NL)