(19)

(11)

EP 4 824 286 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24904799.4 (22) Date of filing: 11.12.2024

(51) International Patent Classification (IPC):  C12Q 1/6886(2018.01) G01N 33/574(2006.01) G16H 50/20(2018.01) C12N 15/11(2006.01) G16B 40/00(2019.01) (52) Cooperative Patent Classification (CPC): C12Q 1/6886; G16B 20/20; G16H 10/40; G16B 25/20; G16B 40/20; C12Q 2600/154 (86) International application number: PCT/US2024/059548 (87) International publication number: WO 2025/128691 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 12.12.2023 US 202363609140 P (71) Applicant: Flagship Pioneering Innovations VI, LLC Cambridge, MA 02142 (US)	(72) Inventor: CHARLTON, Jocelyn Cambridge, MA 02142 (US) (74) Representative: Maiwald GmbH  Elisenhof Elisenstraße 3 80335 München 80335 München (DE)