(19)

(11)

EP 4 824 547 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24904963.6 (22) Date of filing: 13.12.2024

(51) International Patent Classification (IPC):  G01N 33/50(2006.01) G01N 33/68(2006.01) G01N 33/53(2006.01) (52) Cooperative Patent Classification (CPC): G01N 33/689; G01N 2800/368; G01N 2333/705; G01N 2333/521; G01N 2333/525; G01N 2333/495; G01N 2333/70578; G01N 2800/52; G01N 2333/57 (86) International application number: PCT/US2024/060034 (87) International publication number: WO 2025/128997 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 15.12.2023 US 202363610784 P (71) Applicant: Ohio State Innovation Foundation Columbus OH 43210 (US)	(72) Inventor: GILLESPIE, Shannon Columbus, Ohio 43210 (US) (74) Representative: FRKelly  Waterways House Grand Canal Quay Dublin D02 PD39 Dublin D02 PD39 (IE)