SYSTEMS AND METHODS FOR MASKING TREATMENT-AFFECTED REGIONS IN THE GENOME TO IMPROVE CLASSIFIER PERFORMANCE - Patent 4824803

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EP 4 824 803 A1

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(43)	Date of publication:
	21.10.2026 Bulletin 2026/43

(21)	Application number: 24829001.7

(22)	Date of filing: 13.12.2024

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International Patent Classification (IPC):

G16B 40/20^(2019.01)

C12Q 1/6886^(2018.01)

(52)	Cooperative Patent Classification (CPC):
	C12Q 2600/154; G16B 40/20; C12Q 1/6886; G16H 10/60; G16B 20/00; G16B 20/50; C12Q 2600/106

(86)	International application number:
	PCT/US2024/060122

(87)	International publication number:
	WO 2025/129061 (19.06.2025 Gazette 2025/25)

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
	Designated Extension States:
	BA
	Designated Validation States:
	GE KH MA MD TN

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Priority:

14.12.2023 US 202363610143 P

(71)	Applicant: Grail, Inc.
	Menlo Park, California 94025 (US)

(72)	Inventors:
	ZHOU, Yifan Menlo Park, California 94025 (US) MELTON, Collin Menlo Park, California 94025 (US)

(74)	Representative: Murgitroyd & Company
	165-169 Scotland Street Glasgow G5 8PL Glasgow G5 8PL (GB)

(54)	SYSTEMS AND METHODS FOR MASKING TREATMENT-AFFECTED REGIONS IN THE GENOME TO IMPROVE CLASSIFIER PERFORMANCE