1H-Pyrimido-(4,5-c)-1,2-diazepines, methods for their preparation and compositions containing them; their use as intermediates for heterocyclic transformations.

(19)

(11)

EP 0 000 541 A3

(12)	EUROPEAN PATENT APPLICATION

(88)	Date of publication A3:
	11.07.1979 Bulletin 1979/14

(43)	Date of publication A2:
	07.02.1979 Bulletin 1979/03

(21)	Application number: 78100435

(22)	Date of filing: 19.07.1978

(84)	Designated Contracting States:
	BE CH DE FR GB NL SE

(30)

Priority:

20.07.1977 GB 3038077

(71)	Applicant: THE WELLCOME FOUNDATION LIMITED
	()

(72)	Inventors:
	Morrison Jr., Robert William () Mallory, William Revill () Styles, Virgil Lee ()

(54)	1H-Pyrimido-(4,5-c)-1,2-diazepines, methods for their preparation and compositions containing them; their use as intermediates for heterocyclic transformations.

(57) Compounds of the general formula (1)

wherein R' and R² are selected from a lower alkyl group, a phenyl group (optionally substituted by one or more hydroxy or lower alkoxy groups), a pyridyl group or a group -C0₂R where R is a lower alkyl group, (provided that when R' is a group -CO₂R, R²is a lower alkyl group) are disclosed.
The compounds of formula (I) are useful as intermediates to compounds of other ring systems which are of pharmacological interest.
Certain of the compounds of formula (I) are also useful as antimicrobial agents.

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