(19)
(11) EP 1 707 192 A3

(12) EUROPEAN PATENT APPLICATION

(88) Date of publication A3:
18.10.2006 Bulletin 2006/42

(43) Date of publication A2:
04.10.2006 Bulletin 2006/40

(21) Application number: 06111360.1

(22) Date of filing: 17.03.2006
(51) International Patent Classification (IPC): 
A61K 9/16(2006.01)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR MK YU

(30) Priority: 30.03.2005 IT MI20050517

(71) Applicant: THERAPICON SRL
I-20146 Milan (IT)

(72) Inventors:
  • Veronesi, Paolo Alberto
    20146 Milan (IT)
  • Veronesi, Anna Maria
    20146 Milan (IT)

(74) Representative: Rickard, David John 
26 Mallinson Road
London SW11 1BP
London SW11 1BP (GB)

   


(54) Pharmaceutical composition


(57) The present invention relates to a pharmaceutical composition characterized in that it contains an active ingredient comprising two or more flavonoids in microcrystalline form, wherein the two or more microcrystalline flavonoids comprise diosmin and at least one other flavonoid; and further wherein the two or more microcrystalline flavonoids exhibit the following characterizing parameters :
(a) a specific surface area of 4 to 18 m2/g, according to BET determination;
(b) an F/D (F=other flavonoids/D=diosmin) (weight/weight) ratio of from 0.03 to 0.1; and
(c) a moisture content of less than 4.0 % by weight.







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