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EUROPEAN PATENT SPECIFICATION |
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Mention of the grant of the patent: |
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11.08.2010 Bulletin 2010/32 |
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Date of filing: 27.10.2000 |
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International Patent Classification (IPC):
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International application number: |
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PCT/US2000/029705 |
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International publication number: |
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WO 2001/030505 (03.05.2001 Gazette 2001/18) |
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CIRCUMFERENTIALLY DRIVEN CONTINUOUS FLOW CENTRIFUGE
AM UMFANG ANGETRIEBENE DURCHFLUSSZENTRIFUGE
CENTRIFUGEUSE A FLUX CONTINU ET A ENTRAINEMENT CIRCONFERENTIEL
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Designated Contracting States: |
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AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
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Priority: |
28.10.1999 US 162320 P
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Date of publication of application: |
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08.01.2003 Bulletin 2003/02 |
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Proprietor: Velico Medical, Inc. |
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Beverly MA 01915-6122 (US) |
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Inventors: |
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- AITKENHEAD, William
Sharon, MA 02067 (US)
- JORGENSEN, Glen
Marlboro, MA 01752 (US)
- STANDLEY, Robert, L.
Belmont, MA 02478 (US)
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Representative: Murphy, Colm Damien et al |
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Ipulse
26 Mallinson Road London
SW11 1BP London
SW11 1BP (GB) |
| (56) |
References cited: :
US-A- 2 832 374 US-A- 3 646 972 US-A- 4 163 519 US-A- 4 372 484 US-A- 4 425 112 US-A- 4 865 081 US-A- 5 665 048
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US-A- 3 586 413 US-A- 4 018 304 US-A- 4 221 322 US-A- 4 389 206 US-A- 4 459 169 US-A- 5 431 814
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| Note: Within nine months from the publication of the mention of the grant of the European
patent, any person may give notice to the European Patent Office of opposition to
the European patent
granted. Notice of opposition shall be filed in a written reasoned statement. It shall
not be deemed to
have been filed until the opposition fee has been paid. (Art. 99(1) European Patent
Convention).
|
BACKGROUND OF THE INVENTION
[0001] The present invention relates to centrifuge apparati and more particularly to a centrifuge
which works in conjunction with a cassette, rotor or other device having fluid retentive
chambers and fluid flow tubing fixedly attached to the axis of the device.
[0002] In the context of mechanisms which have come to be known as continuous flow centrifuges,
when a length of tubing is fixedly attached to the rotation axis of a device which
contains the fluid material to be centrifuged, the entire length of tubing must be
rotated by use of rotary seals or some other means to avoid twisting the tubing. A
well known method for avoiding the use of rotary seals is to curve the length of tubing
outwardly from the axis and around the outer edge of the circumference of the rotor,
cassettes or the like and, to rotate the tubing in an orbital fashion around the rotor/cassette
at one-half times the rotational speed of the rotor/cassette itself. Such a method
for eliminating tube twisting and apparati therefore are disclosed, for example, in
U.S. Pat. Nos. 4,216,770,
4,419,089 and
4,389,206.
[0003] Problems inherent in such prior apparatuses which orbit the fluid flow tubing around
the axis of centrifuge rotation are that the axis of rotation is disposed vertically,
the tubing is routed through an axial shaft and the apparatus is driven by driving
an axial shaft which requires a high aspect ratio and an elongated shaft which limit
the rotational speed, render the apparatus instable and limits the ability of the
user to mount a second cassette, rotor or the like on opposing sides of the chuck
component of the apparatus.
[0004] In accordance with the foregoing, reference is also made to
U.S. Pat. No. 5,665,048 that provides a centrifuge for rotating a fluid retentive housing having fluid input
and output tubing fixedly connected to a rotation axis of the fluid retentive housing,
the centrifuge comprising: a frame; a first rotatable mechanism having a rotation
axis, the fluid retentive housing being coaxially mounted thereon for co-rotation
therewith; a second rotatable mechanism having a rotation axis, the first and second
rotation mechanism being coaxially mounted on the frame; the second rotatable mechanism
having an outer circumferential surface engaged with a drive mechanism, the drive
mechanism driving the outer circumferential surface such that the second rotatable
mechanism rotates at a selected rotational speed X; the first rotatable mechanism
being interconnected to the second rotatable mechanism such that the first rotatable
mechanism rotates simultaneously with the second rotatable mechanism at a rotational
speed of 2X.
[0005] The second rotatable mechanism includes a seat for holding a distal length of the
output tubing which extends from the axis of the fluid retentive housing, wherein
the distal length of the output tubing held by the seat is rotated around the rotation
axis at the same rotational speed as the second rotatable mechanism. One of the problems
associated with such an arrangement is that there is continuous friction between the
tubing and the seat.
[0006] US5431814 discloses a rotary filtration apparatus for separating a selected material suspended
in a fluid, the apparatus comprising a housing having a selected axis of rotation,
the housing being rotatably mounted on a rotation device which rotates the housing
about the selected axis of rotation of the housing; the housing sealably enclosing
and defining a fluid sealed cavity extending radially outwardly from the axis of the
housing; a filter mounted within the cavity of the housing such that the cavity is
divided into at least a first fluid retentive input chamber and a second fluid retentive
output chamber, the input and output chambers being disposed on opposite sides of
the filter; a fluid input line sealably communicating with the fluid input chamber
for feeding the material suspended in the fluid into the input chamber under a selected
pressure; the filter being selectively permeable to the fluid under the selected pressure
and selectively impermeable to the selected material under the selected pressure,
the fluid being fed into the input chamber flowing through the filter and into the
output chamber under the selected pressure; a fluid output line sealably communicating
with the input chamber for receiving and routing fluid which is fed into the input
chamber out of the input chamber; the rotation device drivably rotating the housing
around the axis such that the material suspended in the fluid in the input chamber
is forced to travel under centripetal force in a radially outward direction from the
axis.
[0007] US4865081 discloses a multi-lumen tube arrangement for use in a sliding-seal-free centrifuge
comprising a plurality of equilength individual tubes which after a twisting about
the longitudinal axis of the tube arrangement are each held fixed free of tension
at their ends.
[0008] US2832374 discloses a flexible conduit assembly comprising spaced, pierced flange members,
a plurality of flexible tubes secured at each end thereof to one of said flanges in
register with an opening therein, said tubes being helically disposed about one another.
[0009] US3646972 discloses information transmitting systems including a plurality of tubular members
for pneumatically or hydraulically passing data in pulse form; the tubular members
being stranded about a core member which may be tubular or in electric cable form,
the tubular members being stranded with a reverse lay to allow such members to be
displaced to allow convenient tapping of the tubular members or the core member.
[0010] US4018304 discloses a lubrication system for a centrifugal liquid processing apparatus or the
like having a bearing subject to operation in a centrifugal force field includes a
reservoir wherein a quantity of fluid lubricant to be applied to the bearing is contained,
an accumulator for receiving lubricant from the bearing, a first flow path from the
reservoir through the bearing to the accumulator, and a second flow path from the
accumulator to the reservoir. During operation of the apparatus lubricant is forced
by the centrifugal force field to flow along the first flow path from the reservoir,
through the bearing and into the accumulator under pressure. When the apparatus is
stopped, lubricant is forced to return from the accumulator along the second flow
path to the reservoir. An orifice is provided in the first flow path to control the
flow and pressure of the lubricant within the bearing, and check valves are provided
to restrict the lubricant to a circulating route through the bearing.
[0011] US4163519 discloses a 2:1 compensating rotor is used in a continuous-flow centrifuge system,
thereby allowing the dynamic loading and unloading of biological suspensions and processing
solutions in a "closed" fashion without resort to rotary seals. Improved high speed
performance is obtained by utilization of an inherently symmetrical load sharing epicyclic
reverted gear train. The effective lifetime of the component gears is increased due
to the load sharing feature of the symmetrical epicyclic reverted gear train.
[0012] US4221322 discloses a 2:1 compensating rotor is used in a continuous-flow centrifuge system,
thereby allowing the dynamic loading and unloading of biological suspensions and processing
solutions in a "closed" fashion without resort to rotary seals. Improved performance
is obtained by relieving the mechanical stresses associated with the 2:1 relative
motion between rotary components. In zones of high flexural and torsional stress low-friction
bearing mounted tube constraint fittings are utilized to minimize tubing loop wear
and risk of rupture. Similarly, in regions of high centrifugal force a tube guide
insert is utilized to separate and constrain the discrete fluid-carrying tubes, thereby
minimizing abrasion induced by the relative motion between the discrete tubes, as
well as minimizing abrasion induced by the relative motion between the discrete tubes
and the inner walls of the tube guide assembly.
[0013] US4425112 discloses a flow-through centrifuge free of rotating seals. The centrifuge includes
a frame having three spaced apart horizontal plates which carry a central bowl, a
countershaft and a tube-supporting hollow shaft. A motor is arranged to drive the
frame at an angular velocity of omega. The countershaft is driven by a stationary
pulley on the motor and drives the bowl at an angular velocity of 2 omega. The motion
of the countershaft is also transferred to the tube-supporting hollow shaft by a pulley
coupling having a ratio which effects rotation of the hollow shaft, with respect to
the frame, at an angular velocity of - omega.
[0014] US4459169 discloses a rotatable processing bowl assembly adapted for mounting in a centrifuge
includes an umbilical tubing system formed of a plurality of individual flexible tubes
each of which communicates with the processing bowl. Each tube has an exterior wall
and includes a first portion extending adjacently from the bowl and a second portion
which is spaced from the bowl. The exterior walls of the tubes are bonded together
along their first portions so that the joined exterior walls collectively define the
outer periphery of the tubing system along the first portions of the tubes. Preferably,
the tubes are also wound to form a predetermined helical pattern along their first
portions. This arrangement enhances the tubing system's durability and resistance
to fatigue along the bonded together first portions, particularly at higher rotational
speeds, and permits direct, facile connection of the free and unattached second portions
with external apparatus.
SUMMARY OF THE INVENTION
[0015] Therefore, in accordance with the present invention, there is provided an improvement
in a centrifuge, and, in particular, an improvement relating to fluid tubing by the
support thereof. In accordance with the present invention, there is provided a centrifuge
for rotating a fluid retentive housing as defined in either of claims 12 or 24.
[0016] In accordance with another aspect of the present invention, there is provided a multi-lumen
rope comprising a plurality of elongated tubes as defined in claim 1.
[0017] Preferred embodiments are given in the dependent claims.
BRIEF DESCRIPTION OF THE DRAWINGS
[0018]
FIG. 1 is a perspective view of a centrifuge apparatus according to the invention;
FIG. 2 is a perspective view of a portion of the apparatus of FIG. 1, particularly,
the support arm;
FIG. 3 is an exploded perspective view showing the support arm with end guides and
the fluid retentive housing with fluid tubing;
FIG. 4 is an exploded perspective view showing the components of the fluid retentive
housing and fluid tubing; and
FIGS. 5A-5H disclose various separate embodiments of the fluid tubing or multilumen
rope as in accordance with the present invention.
DETAILED DESCRIPTION
[0019] FIG. 1 shows a centrifuge apparatus 10, the basic construction of which may be substantially
the same as that described in
U. S. Pat. No. 5,665,048. As far as the invention of the present invention is concerned, this relates more
to the tubing 70, and, in particular, its support from the centrifuge apparatus 10.
The support includes the support arm 50 as well as its guide members 52 and 54.
[0020] As indicated previously, the basic structure of the centrifuge apparatus 10 may be
the same as that described in
U. S. Pat. No. 5,665,048.
U. S. Pat. No. 5,665,048 is thus hereby now incorporated by reference herein. This apparatus includes a bag
set 20. This may also be referred to as aself-contained fluid retentive centrifuge
cassette or rotor which is mounted on an inner-rotatable chuck 60. The bag set 20,
as illustrated in FIGS. 1 and 3, has fluid input and output 70 coaxially and fixedly
attached to the axis 40 of the cassette 20. As shown, the cassette is mounted on the
chuck 60 such that it's rotation axis is coaxial along common axis 40. Thus, as the
chuck 60 rotates, the fixedly attached tubing 70 co-rotates therewith. As shown, there
is a length 72 of the tubing 70 which extends axially outwardly from the area of the
fixed attachment 71. The length 72 of tubing is curved axially backwardly toward and
extends through a radially outer, separately rotatable pulley 90 which rotates, by
virtue of a gear train interconnecting the pulley 90 and the chuck 60 at a speed of
XRPM while the chuck rotates at a speed of 2XRPM. Again, reference is made to
U.S. Pat. No. 5,665,048 which is incorporated by reference herein regarding the operation of the chuck and
pulley arrangement. FIG. 1 actually shows the cutaway section indicating the chuck
60 and a further cutaway section showing a gear 91, part of the aforementioned gear
train.
[0021] In operation, as the pulley 90 rotates, the backwardly curved length 72 of the tubing
is rotated around axis 40 at a rate of XRPM while the fixedly attached end 71 of the
tubing 70 is actually rotated at a rate of 2XRPM. This phenomenon is well known in
the art as enabling the tubing 70 to avoid twisting around its axis even as the cassette
20 and the chuck 60 forced the tubing 70, 71 to be axially rotated. A fuller description
of this phenomenon is described in
U.S. Pat. No. 5,665,048 as well as in
U.S. Pat. No. RE29,738 (
3, 586, 413) (Adams).
[0022] Now, reference is further made to FIGS. 2 and 3 which illustrate the support arm
50. The support arm 50 at its central section 56, is fixedly attached to an inner-periphery
of the pulley 90. Thus, the support arm 50 rotates with the Hub 90.
[0023] The support arm 50 is of elongated shape and extends on either side of the centrifuge
apparatus 10, as illustrated in FIG. 1. As illustrated in FIG. 2, the support arm
50 has an elongated channel 58 which receives the support tube 80. The support tube
80 is actually supported in the channel 58 by means of a pair of bearings 82 illustrated
in FIGS. 3 and 4. Each of these bearings is accommodated in a corresponding recess
84 at opposite ends of the support arm, as illustrated in FIG. 2.
[0024] Thus, the support arm 50 is fixedly attached to the pulley 90, the support tube 80
is supported within the channel and support arm by means of bearings 82 and then the
fluid tubing 70 extends through the support tube 80, but in this regard, FIG. 1 shows
all of these various components in their final assembled state. The fluid tubing 70
is shown being guided by a C-shaped guide member 52 into one end of the support tube
80. At the other end of the support tube, the fluid tubing length 72 extends out of
the support tube and into the S-shaped tubing guide 54, as also illustrated in FIG.
1.
[0025] When the fluid tubing is in the form of a multi-lumen rope, embodiments of which
will be described hereinafter, the elements of the rope furthest from the access of
rotation exert large forces against the supporting surface and consequently produce
large frictional forces impeding the twists required to make the slip rope function.
It has been found that the following perimeters are desirable for proper operation
of a multi-lumen skip rope;
- 1) strong but flexible skip rope assembly;
- 2) ability to transmit torque without damage to the rope;
- 3) low friction between rope and supports particularly far from the rotational axis
where the g-field is high.
[0026] Parameters 1 and 2 are generally met by selecting relatively small diameter, high
durometer thermoplastic tubing. Gluing methods and fixtures were used so that an assembly
of at least 9 lumens could be well fabricated with very uniform tubing lay and therefore
stiffness and strength. This assembly is of a spiral wrapped construction to improve
uniformity.
[0027] Reference is also now made to FIGS. 5A-5H for various designs of the rope. FIG. 5A
shows a single strand 100A counterclockwise wrap while FIG. 5B shows a multi-strand
100B counterclockwise wrap. FIG. 5C shows a single strand 100C clockwise wrap, while
FIG. 5D shows a multi-strand 100D clockwise wrap. Through testing and observation,
it is found that the two ends of the skip rope behave asymmetrically. This is due
to the fact that one end is twisting clockwise and the other end counterclockwise.
One end tends to twist up while the other end untwists. Thus, it has been found that
in accordance with one embodiment, during the rope fabrication, the twist direction
may be reversed in mid-rope. In this regard, refer to FIGS. 5A, 5F and 5H. It is noted
that a small section of the rope in the middle has no twist. By doing so, one may
install the rope so that both ends see the same twisting condition. The rope may be
installed so that both ends twist up to yield maximum torque stiffness so that both
ends untwist to produce minimum restriction to fluid flow in the tubes.
[0028] In accordance with the present invention, in order to provide the desired low friction,
relating to the fluid tubing, it is noted that portions of the skip rope progress
through curved supports from the access of rotation from the periphery where the rope
is guided through very smooth, Teflon, hard coated aluminum parts. Please refer to
FIG. 3 and guide members 52 and 54. That in these areas, the co-efficient of friction
between the skip rope and the guides is preferably less than 0.2.
[0029] The portion of the skip rope at the maximum radius from the center of rotation is
a straight section of various lengths. This section can be very important to the overall
torque needed to twist the rope. Indeed the weight of the skip rope assembly (plus
fluids if it is filled) is increased by the G-field which may be a multiplier of 1,000
or more. To reduce the torque needed to drive the twisting motion, this section of
skip rope is supported by the aforementioned support tube 80. This is preferably a
stiff tube of either metal of structural plastic. The stiff tube is itself supported
by the aforementioned low friction bearings 82 allowing full rotation about its own
axis. This reduces the torque needed to drive this region of the skip rope assembly
to very nearly zero. This structure of the support tube and bearings, provides an
advantageous support for the length of fluid tubing or lumen between the guides 52
and 54. Because the support tube is free to rotate, upon rotation of the members such
as 60 and 90 in FIG. 1, in other words first and second rotation mechanisms, the fluid
tubing is free to either rotate with or rotate relative to the support tube.
[0030] Another characteristic of the present invention relates to the construction of the
multilumen rope itself, as illustrated, for example, in FIG.5B. This may be comprised
of a plurality of at least eight lumens 100B about a center lumen 102B. The center
lumen 102B is straight while the other peripheral lumens wrap, such as illustrated
in FIG.5B. The center lumen 102B may be an expresser tube while the lumens100B may
be processing tubes. Put another way, the tube 102B may be an input tubing and tubings
100B may be output tubings. The input and output tubings may be also reversed.
[0031] It will now be apparent to those skilled in the art that other embodiments, improvements,
details and uses can be made consistent with the following claims.
1. A combination of a multi-lumen rope, fluid retaining mechanism, a rotor (20), a support
arm (50), a support tube (80) and a bearing member (82) comprising a plurality of
elongated tubes the multi-lumen rope (100B; 102B) suitable for delivering one or more
fluids between a first fluid retaining mechanism and a fluid receiving rotatably driven
rotor (20), one end of the rope being attached to the center of the driven rotor (20),
the other end of the rope being attached to the first fluid retaining mechanism, the
first fluid retaining mechanism being mounted on an opposing side of the rotor (20)
and such that the point of attachment of the other end of the rope is substantially
coaxial with an axis (40) of the rotor (20), characterised in that, said support arm (50) is rotatable with the rotor (20), said support tube (80) can
receive therethrough at least part of the distal length of the elongated tubes (100B;
102B), and wherein a guide member is provided, which is a C-shaped or S-shaped guide
member (52; 54) secured to one side of said support arm (50), and said bearing member
(82) rotatably supports said support tube (80) in said support arm (50).
2. A combination as set forth in claim 1, wherein said support arm (50) has a channel
for receiving said support tube (80) and opposite recesses for receiving a pair of
bearings that comprise said bearing member.
3. A combination as set forth in claim 1 or 2, further including another guide member
secured to the other end of said support arm.
4. A combination as set out in claim 1 wherein said elongated tubes (100B; 102B) comprise
at least one tube disposed in a spiral wrap.
5. A combination as set forth in claim 4, wherein said plurality of tubes include a center
expresser tube and a plurality of peripheral processing tubes.
6. A combination as set forth in claim 4 or 5, wherein said spiral wrap is counterclockwise.
7. A combination as set forth in claim 4 or 5, wherein said spiral wrap is clockwise.
8. A combination as set forth in claim 4 or 5, wherein one end of the rope has a right
hand twist and the other end of the rope has a left hand twist.
9. A combination as set forth in claim 8, wherein a section of the rope in the middle
has no twist.
10. A combination as set forth in any of claims 4 to 9, wherein the rope is installed
so that both ends twist up to yield maximum tortional stiffness.
11. A combination as set forth in claims 4 to 10, wherein the rope is installed so that
both ends untwist to produce minimum restriction to fluid flow in the tubes.
12. A centrifuge (10) for rotating a fluid retentive housing (20) such that one or more
selected materials suspended in a fluid retained within the housing are centrifuged
upon rotation of the housing, said centrifuge (10) including: a first rotatable mechanism
(60) having a rotation axis with the fluid retentive housing (20) being coaxially
mounted on the first rotatable mechanism for co-rotation therewith; a second rotatable
mechanism (90) having a rotation axis with the first and second rotatable mechanisms
being coaxially interconnected for co-rotation around a common axis (40); fluid tubing
(70) connected to the axis (40) of the fluid retentive housing (20) and having a distal
length (72) that extends axially outwardly from the fluid retentive housing; characterized by a support arm (50) mounted to the second rotatable mechanism (90), a support tube
(80) for receiving therethrough at least part of the distal length (72) of said fluid
tubing (70), a guide member where said guide member is a C-shaped or S-shaped guide
member (52; 54) secured to one side of said support arm (50) and a bearing member
(82) for rotatably supporting said support tube (80) in said support arm, whereby
upon rotation of said first and second rotation mechanisms said fluid tubing (70)
is free to one of rotate with and rotate relative to said support tube (80).
13. A centrifuge (10) as set forth in claim 12, wherein said support arm (50) extends
to either side of said first and second rotatable mechanisms.
14. A centrifuge (10) as set forth in claim 12, wherein said support arm (50) includes
a longitudinal channel for receiving said support tube (80).
15. A centrifuge (10) as set forth in claim 14, wherein said support arm (50) also includes
oppositely disposed recesses for receiving said bearing member.
16. A centrifuge (10) as set forth in claim 15, wherein said bearing member (82) comprises
a pair of oppositely disposed bearings received in said recesses of said support arm
(50) and for supporting opposite ends of said support tube (80).
17. A centrifuge (10) as set forth in claim 16, wherein said C-shaped guide member (52)
is an input guide member.
18. A centrifuge (10) as set forth in claim 17, including an output S-shaped guide member
(54) secured to an opposite end of said support arm.
19. A centrifuge (10) as set forth in claim 12, wherein said C-shaped guide member (52)
is an input guide member.
20. A centrifuge (10) as set forth in claim 12, including an S-shaped output guide member
(54) secured to an opposite end of said support arm.
21. A centrifuge (10) as set forth in claim 12, wherein said fluid tubing comprises a
high durometer urethane tubing.
22. A centrifuge (10) as set forth in claim 12, further including another C-shaped or
S-shaped guide member (52; 54) at an opposite end of said support arm.
23. A centrifuge (10) as set forth in claim 12, wherein said pair of guide members are
each smooth, Teflon, hardcoated, aluminum members.
24. A centrifuge (10) as set forth in claim 12, further comprising: a frame; the first
rotatable mechanism (60) having a rotation axis (40) and a first diameter, the second
rotatable mechanism (90) having a rotation axis and a second diameter greater than
the first diameter, the first and second rotatable mechanisms being coaxially mounted
on the frame; the second rotatable mechanism (90) having an outer circumferential
surface (91) engaged with a drive mechanism, the drive mechanism driving the outer
circumferential surface such that the second rotatable mechanism (90) rotates at a
selected rotational speed X; the first rotatable mechanism (60) being interconnected
to the second rotatable mechanism (90) such that the first rotatable mechanism rotates
simultaneously with the second rotatable mechanism at a rotational speed of 2X.
25. A centrifuge (10) as set forth in claim 24, wherein said support arm (50) has a channel
for receiving said support tube (80) and opposite recesses for receiving a pair of
bearings that comprise said bearing member.
26. A centrifuge (10) as set forth in claim 25, further including another S-shaped guide
member (54) secured to the other end of said support arm.
1. Kombination aus einem Multi-Lumen-Seil, einem Fluidhaltemechanismus, einem Rotor (20),
einem Stützarm (50), einem Stützrohr (80) und einem Lagerelement (82), wobei das Multi-Lumen-Seil
eine Vielzahl von länglichen Rohren (100B; 102B) umfasst, die für die Zufuhr eines
oder mehrerer Fluide zwischen einem ersten Fluidhaltemechanismus und einem drehbar
angetriebenen, Fluid empfangenden Rotor (20) geeignet ist, wobei ein Ende des Seils
an der Mitte des angetriebenen Rotors (20) und das andere Ende des Seils an dem ersten
Fluidhaltemechanismus angebracht ist, der erste Fluidhaltemechanismus an einer gegenüberliegenden
Seite des Rotors (20) befestigt ist, so dass der Befestigungspunkt des anderen Endes
des Seils im Wesentlichen koaxial zu der Achse (40) des Rotors (20) verläuft, dadurch gekennzeichnet dass der Stützarm (50) mit dem Rotor (20) drehbar ist, das Stützrohr (80) mindestens einen
Teil der distalen Länge der länglichen Rohre (100B; 102B) dort hindurch empfangen
kann, und wobei ein Führungselement bereitgestellt ist, das ein C-förmiges oder S-förmiges
Führungselement (52; 54) ist, das an einer Seite des Stützarms (50) befestigt ist,
und das Lagerelement (82) das Stützrohr (80) in dem Stützarm (50) drehbar stützt.
2. Kombination nach Anspruch 1, wobei der Stützarm (50) einen Kanal für den Empfang des
Stützrohrs (80) sowie gegenüberliegende Vertiefungen für den Empfang eines Paars Lager,
die das Lagerelement umfassen, aufweist.
3. Kombination nach Anspruch 1 oder 2, die des Weiteren ein anderes Führungselement umfasst,
das an dem anderen Ende des Stützarms befestigt ist.
4. Kombination nach Anspruch 1, wobei die länglichen Rohre (100B; 102B) mindestens ein
Rohr umfassen, das als spiralförmige Umwicklung angeordnet ist.
5. Kombination nach Anspruch 4, wobei die Vielzahl der Rohre ein zentrales Ausdrückrohr
und eine Vielzahl von umfänglichen Verarbeitungsrohren umfasst.
6. Kombination nach Anspruch 4 oder 5, wobei die spiralförmige Umwicklung gegen den Uhrzeigersinn
angeordnet ist.
7. Kombination nach Anspruch 4 oder 5, wobei die spiralförmige Umwicklung im Uhrzeigersinn
angeordnet ist.
8. Kombination nach Anspruch 4 oder 5, wobei ein Ende des Seils einen Rechtsdrall und
das andere Ende des Seils einen Linksdrall aufweist.
9. Kombination nach Anspruch 8, wobei ein Abschnitt des Seils in der Mitte keinen Drall
aufweist.
10. Kombination nach Anspruch 4 bis 9, wobei das Seil so installiert ist, dass beide Enden
verdrallt sind, um eine maximale Torsionssteifigkeit zu ergeben.
11. Kombination nach Anspruch 4 bis 10, wobei das Seil so installiert ist, dass beide
Enden nicht verdrallt sind, um in den Rohren eine minimale Einschränkung der Fluidströmung
zu erzeugen.
12. Zentrifuge (10) zum Rotieren eines Fluid enthaltenden Gehäuses (20), so dass ein oder
mehrere ausgewählte Materialien, die in einem Fluid suspendiert sind, das in dem Gehäuse
enthalten ist, bei Rotation des Gehäuses zentrifugiert werden, wobei die Zentrifuge
(10) Folgendes umfasst: einen ersten rotierbaren Mechanismus (60), der eine Rotationsachse
aufweist, wobei das Fluid enthaltende Gehäuse (20) an dem ersten rotierbaren Mechanismus
koaxial angebracht ist, um zusammen mit diesem zu rotieren; einen zweiten rotierbaren
Mechanismus (90), der eine Rotationsachse aufweist, wobei der erste und zweite rotierbare
Mechanismus koaxial miteinander verbunden sind, um zusammen um eine gemeinsame Achse
(40) zu rotieren; eine Fluidleitung (70), die mit der Achse (40) des Fluid enthaltenden
Gehäuses (20) verbunden ist und eine distale Länge (72) aufweist, die sich axial auswärts
von dem Fluid enthaltenden Gehäuse erstreckt; gekennzeichnet durch einen Stützarm (50), der an dem zweiten rotierbaren Mechanismus (90) angebracht ist,
ein Stützrohr (80) für den Empfang mindestens eines Teils der distalen Länge (72)
der Fluidleitung (70) dort hindurch, ein Führungselement, wobei das Führungselement
ein C-förmiges oder S-förmiges Führungselement (52; 54) ist, das an einer Seite des
Stützarms (50) befestigt ist, und ein Lagerelement (82), das das Stützrohr (80) in
dem Stützarm drehbar stützt, wobei die Fluidleitung (70) bei Drehung des ersten und
zweiten Rotationsmechanismus entweder mit oder im Verhältnis zu dem Stützrohr (80)
frei rotieren kann.
13. Zentrifuge (10) nach Anspruch 12, wobei sich der Stützarm (50) zu beiden Seiten des
ersten und zweiten rotierbaren Mechanismus erstreckt.
14. Zentrifuge (10) nach Anspruch 12, wobei der Stützarm (50) einen Längskanal für den
Empfang des Stützrohrs (80) umfasst.
15. Zentrifuge (10) nach Anspruch 14, wobei der Stützarm (50) ebenfalls gegenüberliegend
angeordnete Vertiefungen für den Empfang des Lagerelements umfasst.
16. Zentrifuge (10) nach Anspruch 15, wobei das Lagerelement (82) ein Paar gegenüberliegend
angeordnete Lager umfasst, die in den Vertiefungen des Stützarms (50) aufgenommen
werden, um gegenüberliegende Enden des Stützrohrs (80) zu stützen.
17. Zentrifuge (10) nach Anspruch 16, wobei das C-förmige Führungselement (52) ein Eingangsführungselement
ist.
18. Zentrifuge (10) nach Anspruch 17, die ein S-förmiges Ausgangsführungselement (54)
umfasst, das an einem gegenüberliegenden Ende des Stützarms befestigt ist.
19. Zentrifuge (10) nach Anspruch 12, wobei das C-förmige Führungselement (52) ein Eingangsführungselement
ist.
20. Zentrifuge (10) nach Anspruch 12, die ein S-förmiges Ausgangsführungselement (54)
umfasst, das an einem gegenüberliegenden Ende des Stützarms befestigt ist.
21. Zentrifuge (10) nach Anspruch 12, wobei die Fluidleitung eine Urethanleitung mit einem
hohen Härtegrad umfasst.
22. Zentrifuge (10) nach Anspruch 12, die des Weiteren ein anderes C-förmiges oder S-förmiges
Führungselement (52; 54) an einem gegenüberliegenden Ende des Stützarms umfasst.
23. Zentrifuge (10) nach Anspruch 12, wobei das Paar Führungselemente jeweils ein glattes
hartbeschichtetes Teflon-Aluminiumelement ist.
24. Zentrifuge (10) nach Anspruch 12, die des Weiteren Folgendes umfasst: einen Rahmen,
wobei der erste rotierbare Mechanismus (60) eine Rotationsachse (40) und einen ersten
Durchmesser aufweist, der zweite rotierbare Mechanismus (90) eine Rotationsachse und
einen zweiten Durchmesser aufweist, der größer als der erste Durchmesser ist, der
erste und zweite rotierbare Mechanismus koaxial an dem Rahmen angebracht sind, der
zweite rotierbare Mechanismus (90) eine äußere Umfangsfläche (91) aufweist, die in
einen Antriebsmechanismus eingreift, wobei der Antriebsmechanismus die äußere Umfangsfläche
so antreibt, dass sich der zweite rotierbare Mechanismus (90) mit einer ausgewählten
Drehzahl X dreht, wobei der erste rotierbare Mechanismus (60) so mit dem zweiten rotierbaren
Mechanismus (90) verbunden ist, dass sich der erste rotierbare Mechanismus gleichzeitig
mit dem zweiten rotierbaren Mechanismus mit einer Drehzahl 2X dreht.
25. Zentrifuge (10) nach Anspruch 24, wobei der Stützarm (50) Folgendes aufweist: einen
Kanal für den Empfang des Stützrohrs (80) und gegenüberliegende Vertiefungen für den
Empfang eines Paars Lager, die das Lagerelement umfassen.
26. Zentrifuge (10) nach Anspruch 25, die des Weiteren ein anderes S-förmiges Führungselement
(54) umfasst, das an dem anderen Ende des Stützarms befestigt ist.
1. Combinaison d'un mécanisme de retenue de fluide à fil multi-lumière, d'un rotor (20),
d'un bras de support (50), d'un tube-support (80) et d'un élément de palier (82) composé
d'une pluralité de tubes allongés (100B ; 102B), le fil multi-lumière pouvant distribuer
un ou plusieurs fluides entre un premier mécanisme de retenue de fluide et un rotor
récepteur de fluide entraîné en rotation (20), une extrémité du fil étant fixée au
centre du rotor entraîné (20) et l'autre extrémité étant fixée au premier mécanisme
de retenue de fluide, le premier mécanisme de retenue de fluide étant installé sur
un côté opposé du rotor (20) de telle sorte que le point de fixation de l'autre extrémité
du fil est essentiellement coaxial à un axe (40) du rotor (20), caractérisée en ce que ledit bras de support (50) peut entrer en rotation avec le rotor (20), ledit tube-support
(80) peut loger à l'intérieur au moins une partie de la longueur distale des tubes
allongés (100B ; 102B), et dans laquelle est fourni un élément de guide (52 ; 54)
en forme de C ou de S fixé solidement à un côté dudit bras de support (50), et ledit
élément de palier (82) soutient en rotation ledit tube-support (80) dans ledit bras
de support (50).
2. Combinaison selon la revendication 1, dans laquelle ledit bras de support (50) dispose
d'un canal permettant de loger ledit tube-support (80), et de renfoncements opposés
permettant de loger une paire de paliers comprenant ledit élément de palier.
3. Combinaison selon la revendication 1 ou 2, comprenant en outre un autre élément de
guide fixé solidement à l'autre extrémité dudit bras de support.
4. Combinaison selon la revendication 1, dans laquelle lesdits tubes allongés (100B ;
102B) comprennent au moins un tube enroulé en hélice.
5. Combinaison selon la revendication 4, dans laquelle ladite pluralité de tubes comprend
un tube d'expression central et une pluralité de tubes de traitement périphériques.
6. Combinaison selon la revendication 4 ou 5, dans laquelle ladite hélice est enroulée
dans le sens inverse des aiguilles d'une montre.
7. Combinaison selon la revendication 4 ou 5, dans laquelle ladite hélice est enroulée
dans le sens des aiguilles d'une montre.
8. Combinaison selon la revendication 4 ou 5, dans laquelle une extrémité du fil est
tordue à droite et l'autre extrémité du fil est tordue à gauche.
9. Combinaison selon la revendication 8, dans laquelle une section du fil au milieu n'est
pas tordue.
10. Combinaison selon l'une quelconque des revendications 4 à 9, dans laquelle le fil
est installé de telle sorte que les deux extrémités se tordent jusqu'à un niveau de
rigidité en torsion maximal.
11. Combinaison selon les revendications 4 à 10, dans laquelle le fil est installé de
telle sorte que les deux extrémités se déroulent pour créer des restrictions de débit
de fluide minimales dans les tubes.
12. Centrifugeuse (10) permettant de faire tourner une enceinte de retenue de fluide (20)
de telle sorte qu'une ou plusieurs matières sélectionnées mises en suspension dans
un fluide retenu dans l'enceinte sont centrifugées lorsque l'enceinte est en rotation,
ladite centrifugeuse (10) comprenant : un premier mécanisme rotatif (60) muni d'un
axe de rotation, l'enceinte de retenue de fluide (20) étant installée de manière coaxiale
sur le premier mécanisme rotatif afin de permettre une co-rotation avec celui-ci ;
un deuxième mécanisme rotatif (90) muni d'un axe de rotation, les premier et deuxième
mécanismes rotatifs étant interconnectés de manière coaxiale afin de permettre une
co-rotation autour d'un axe commun (40) ; des tubes de fluide (70) connectés à l'axe
(40) de l'enceinte de retenue de fluide (20) et présentant une longueur distale (72)
s'étendant dans une direction axiale vers l'extérieur de l'enceinte de retenue de
fluide ; caractérisée par un bras de support (50) installé sur le deuxième mécanisme rotatif (90), un tube-support
(80) permettant de loger à l'intérieur au moins une partie de la longueur distale
(72) desdits tubes de fluide (70), un élément de guide en forme de C ou de S (52 ;
54) fixé solidement à un côté dudit bras de support (50) et un élément de palier (82)
permettant de soutenir en rotation ledit tube-support (80) dans ledit bras de support,
dans laquelle, lors de la rotation desdits premier et deuxième mécanismes rotatifs,
lesdits tubes de fluide (70) sont libres soit d'entrer en rotation avec ledit tube-support
(80), soit d'entrer en rotation par rapport à celui-ci.
13. Centrifugeuse (10) selon la revendication 12, dans laquelle ledit bras de support
(50) s'étend des deux côtés desdits premier et deuxième mécanismes rotatifs.
14. Centrifugeuse (10) selon la revendication 12, dans laquelle ledit bras de support
(50) comprend un canal longitudinal permettant de loger ledit tube-support (80).
15. Centrifugeuse (10) selon la revendication 14, dans laquelle ledit bras de support
(50) comprend également des renfoncements disposés de manière opposée et permettant
de loger ledit élément de palier.
16. Centrifugeuse (10) selon la revendication 15, dans laquelle ledit élément de palier
(82) se compose d'une paire de paliers disposés de manière opposée, logés dans lesdits
renfoncements dudit bras de support (50) et permettant de soutenir des extrémités
opposées dudit tube-support (80).
17. Centrifugeuse (10) selon la revendication 16, dans laquelle ledit élément de guide
en forme de C (52) est un élément de guide d'introduction.
18. Centrifugeuse (10) selon la revendication 17, comprenant un élément de guide de sortie
en forme de S (54) fixé solidement à une extrémité opposée dudit bras de support.
19. Centrifugeuse (10) selon la revendication 12, dans laquelle ledit élément de guide
en forme de C (52) est un élément de guide d'introduction.
20. Centrifugeuse (10) selon la revendication 12, comprenant un élément de guide de sortie
en forme de S (54) fixé solidement à une extrémité opposée dudit bras de support.
21. Centrifugeuse (10) selon la revendication 12, dans laquelle lesdits tubes de fluide
se composent de tubes en uréthane à coefficient de dureté élevé.
22. Centrifugeuse (10) selon la revendication 12, comprenant en outre un autre élément
de guide en forme de C ou de S (52 ; 54) au niveau d'une extrémité opposée dudit bras
de support.
23. Centrifugeuse (10) selon la revendication 12, dans laquelle ladite paire d'éléments
de guide est composée d'éléments lisses en aluminium à revêtement dur en téflon.
24. Centrifugeuse (10) selon la revendication 12, comprenant en outre : un châssis ; le
premier mécanisme rotatif (60) étant muni d'un axe de rotation (40) et d'un premier
diamètre ; le deuxième mécanisme rotatif (90) étant muni d'un axe de rotation et d'un
deuxième diamètre plus important que le premier diamètre ; les premier et deuxième
mécanismes rotatifs étant installés de manière coaxiale sur le châssis ; le deuxième
mécanisme rotatif (90) disposant d'une surface circulaire externe (91) en engagement
avec un mécanisme d'entraînement, le mécanisme d'entraînement entraînant la surface
circulaire externe de telle sorte que le deuxième mécanisme rotatif (90) tourne à
une vitesse de rotation sélectionnée X ; le premier mécanisme rotatif (60) étant interconnecté
au deuxième mécanisme rotatif (90) de telle sorte que le premier mécanisme rotatif
tourne en même temps que le deuxième mécanisme rotatif à une vitesse de rotation de
2X.
25. Centrifugeuse (10) selon la revendication 24, dans laquelle ledit bras de support
(50) dispose d'un canal permettant de loger ledit tube-support (80), et de renfoncements
opposés permettant de loger une paire de paliers comprenant ledit élément de palier.
26. Centrifugeuse (10) selon la revendication 25, comprenant en outre un autre élément
de guide en forme de S (54) fixé solidement à l'autre extrémité dudit bras de support.
REFERENCES CITED IN THE DESCRIPTION
This list of references cited by the applicant is for the reader's convenience only.
It does not form part of the European patent document. Even though great care has
been taken in compiling the references, errors or omissions cannot be excluded and
the EPO disclaims all liability in this regard.
Patent documents cited in the description