Peptides or peptide analogues for modulating the binding of a PDZ protein and a PL protein

(19)

(11)

EP 2 385 124 A3

(12)	EUROPEAN PATENT APPLICATION

(88)	Date of publication A3:
	27.06.2012 Bulletin 2012/26

(43)	Date of publication A2:
	09.11.2011 Bulletin 2011/45

(21)	Application number: 10186068.2

(22)	Date of filing: 12.05.2000

(51)

International Patent Classification (IPC):

C12N 15/12^(2006.01)
C07K 16/28^(2006.01)
C12N 1/21^(2006.01)
C12Q 1/68^(2006.01)
A61K 39/395^(2006.01)

C07K 14/705^(2006.01)
C12N 15/11^(2006.01)
G01N 33/68^(2006.01)
A61K 38/17^(2006.01)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

(30)

Priority:

14.05.1999 US 134114 P
14.05.1999 US 134117 P
14.05.1999 US 134118 P
21.10.1999 US 160860 P
29.10.1999 US 162498 P
13.12.1999 US 170453 P
14.01.2000 US 176195 P
14.02.2000 US 182296 P
11.04.2000 US 547276
11.04.2000 US 196460 P
11.04.2000 US 196528 P
11.04.2000 US 196527 P
11.04.2000 US 196267 P

(62)	Application number of the earlier application in accordance with Art. 76 EPC:
	00932386.6 / 1178817

(71)	Applicant: Arbor Vita Corporation
	Fremont, CA 94555 (US)

(72)	Inventor:
	Lu, Peter Freemont, CA 94555 (US)

(74)	Representative: Broughton, Jon Philip
	avidity IP Merlin House Falconry Court Baker's Lane Epping Essex CM16 5DQ Epping Essex CM16 5DQ (GB)

(54)	Peptides or peptide analogues for modulating the binding of a PDZ protein and a PL protein

(57) The invention provides reagents and methods for inhibiting or enhancing interactions between proteins in hematopoietic cells and other cells involved in the mediation of an immune response. Reagents and methods provided are useful for treatment of a variety of diseases and conditions mediated by immune system cells.

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