(19)
(11) EP 3 839 068 A3

(12) EUROPEAN PATENT APPLICATION

(88) Date of publication A3:
20.10.2021 Bulletin 2021/42

(43) Date of publication A2:
23.06.2021 Bulletin 2021/25

(21) Application number: 20198258.4

(22) Date of filing: 06.10.2010
(51) International Patent Classification (IPC): 
C12Q 1/6883(2018.01)
(52) Cooperative Patent Classification (CPC):
A61P 37/02; A61P 43/00; C12Q 2600/156; C12Q 1/6883; A61P 37/06
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 07.10.2009 US 27851009 P

(62) Application number of the earlier application in accordance with Art. 76 EPC:
17158497.2 / 3219813
10822583.0 / 2486152

(71) Applicant: F. Hoffmann-La Roche AG
4070 Basel (CH)

(72) Inventors:
  • BEHRENS, Timothy W.
    South San Francisco, CA 94080 (US)
  • GRAHAM, Robert R.
    South San Francisco, CA 94080 (US)

(74) Representative: Bernard, Guillaume 
F. Hoffmann-La Roche AG Patent Department Grenzacherstrasse 124
4070 Basel
4070 Basel (CH)


(56) References cited: : 
   
       


    (54) METHODS FOR TREATING, DIAGNOSING, AND MONITORING LUPUS


    (57) Methods of identifying, diagnosing, and prognosing lupus, including certain subphenotypes of lupus, are provided, as well as methods of treating lupus, including certain subpopulations of patients. Also provided are methods for identifying effective lupus therapeutic agents and predicting responsiveness to lupus therapeutic agents.







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