EP 0531342 A4 19940406 -
Publication
Application
Priority
US 52022690 A 19900509
Abstract (en)
[origin: WO9117181A1] A therapeutic peptide comprising between seven and ten amino acid residues, inclusive, the peptide being an analog of one of the following naturally occuring peptides which terminate at the carboxy-terminus with a Met residue: (a) litorin; (b) the ten amino acid carboxy-terminal region of mammalian GRP, neuromedin B, or neuromedin C; and (c) the ten amino acid carboxy-terminal region of amphibian bombesin, said analog being an agonist of one of the naturally occurring peptides.
IPC 1-7
IPC 8 full level
A61K 38/00 (2006.01); A61P 35/00 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 7/64 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); C07K 7/086 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
- [X] US 4331661 A 19820525 - MARKI WALTER E, et al
- [PX] GB 2231051 A 19901107 - ERBA CARLO SPA [IT]
- [PX] WO 9104040 A1 19910404 - BIOMEASURE INC [US]
- [X] L-H WANG ET AL.: "desmethionine alkylamide bombesin analogues: a new class of bombesin receptor antagonists with potent antisecretory activity in pancreatic acini and antimititic activity in Swiss 3T3 cells", BIOCHEMISTRY., vol. 29, no. 3, 23 January 1990 (1990-01-23), EASTON, PA US, pages 616 - 622
- [X] M BROCCARDO ET AL.: "relative potency of bombesin-like peptides", BR. J. PHARMACOL., vol. 55, 1975, BASINGSTOKE, GB, pages 221-227
- [X] N MINAMINO ET AL.: "neuromedin C. a bombesin-like peptide identified in porcine spinal cord", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS., vol. 119, no. 1, 29 February 1984 (1984-02-29), DULUTH, MINNESOTA US, pages 14 - 20
- [PX] L-H WANG ET AL.: "des-met carboxyl-terminally modified analogues of bombesin function as potent bombesin receptor antagonists, partial agonists or agonists", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 265, no. 26, 15 September 1990 (1990-09-15), BALTIMORE, MD US, pages 15695 - 15703, XP000151168
- See references of WO 9117181A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
DOCDB simple family (publication)
WO 9117181 A1 19911114; CA 2081890 A1 19911110; EP 0531342 A1 19930317; EP 0531342 A4 19940406; HU 9203481 D0 19930128; HU T62604 A 19930528; JP H05506862 A 19931007
DOCDB simple family (application)
US 9103265 W 19910509; CA 2081890 A 19910509; EP 91909510 A 19910509; HU 348191 A 19910509; JP 50942891 A 19910509