Global Patent Index - EP 0542928 A4

EP 0542928 A4 19940727 - IMPROVED NON-NUCLEOTIDE-BASED LINKER REAGENTS FOR OLIGOMERS

Title (en)

IMPROVED NON-NUCLEOTIDE-BASED LINKER REAGENTS FOR OLIGOMERS

Publication

EP 0542928 A4 19940727 (EN)

Application

EP 92900694 A 19910809

Priority

US 56530790 A 19900809

Abstract (en)

[origin: WO9202532A1] Novel non-nucleotide reagents for incorporation into oligomers are provided which optionally have a chirally pure skeleton and non-nucleotide reagents are provided which may be coupled into a non-nucleotide/nucleotide polymer. These reagents optionally have a chirally pure skeleton and may include a linker arm to which a detectable label or cross-linking agent may be conjugated.

IPC 1-7

C07H 21/00

IPC 8 full level

C07C 271/22 (2006.01); C07F 9/26 (2006.01); C07H 21/00 (2006.01); C07H 21/04 (2006.01); C12N 15/09 (2006.01); C12Q 1/68 (2006.01)

CPC (source: EP KR)

C07C 271/22 (2013.01 - EP KR); C07F 9/26 (2013.01 - EP KR); C07H 21/00 (2013.01 - EP KR); C07C 2603/18 (2017.04 - EP KR)

Citation (search report)

  • [X] EP 0313219 A2 19890426 - ML TECHNOLOGY VENTURES [US] & WO 8902439 A1 19890323 - ML TECHNOLOGY VENTURES [US]
  • [X] WO 9008156 A1 19900726 - ORIS SA [FR]
  • [DX] P.S.NELSON ET. AL.: "A new and versatile reagent for incorporating multiple primary aliphatic amines into synthetic oligonucleotides", NUCLEIC ACIDS RESEARCH, vol. 17, no. 18, 1989, ARLINGTON, VIRGINIA US, pages 7179 - 7186
  • [DA] C.F.STANFIELD ET. AL.: "Synthesis of protected amino alcohols: a comparative study", JOURNAL OF ORGANIC CHEMISTRY, vol. 46, 1981, EASTON US, pages 4799 - 4800
  • [DA] A.JAGER ET. AL.: "Synthesis of deoxynucleoside methylphosphonates via a phosphonamidite approach", TETRAHEDRON LETTERS, vol. 25, no. 14, 1984, OXFORD GB, pages 1437 - 1440
  • See references of WO 9202532A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IT LI LU NL SE

DOCDB simple family (publication)

WO 9202532 A1 19920220; AU 664542 B2 19951123; AU 9071091 A 19920302; CA 2089087 A1 19920210; EP 0542928 A1 19930526; EP 0542928 A4 19940727; IE 912805 A1 19920212; IL 99068 A0 19920715; IL 99068 A 19980104; JP H05507419 A 19931028; KR 930701468 A 19930611; NZ 239250 A 19931223

DOCDB simple family (application)

US 9108769 W 19910809; AU 9071091 A 19910809; CA 2089087 A 19910809; EP 92900694 A 19910809; IE 280591 A 19910808; IL 9906891 A 19910802; JP 50233791 A 19910809; KR 930700371 A 19930209; NZ 23925091 A 19910802