Global Patent Index - EP 0831875 A4

EP 0831875 A4 20020731 - METHODS OF INHIBITING PHAGOCYTOSIS

Title (en)

METHODS OF INHIBITING PHAGOCYTOSIS

Title (de)

VERFAHREN ZUR HEMMUNG DER PHAGOCYTOSE

Title (fr)

PROCEDES D'INHIBITION DE LA PHAGOCYTOSE

Publication

EP 0831875 A4 20020731 (EN)

Application

EP 96923327 A 19960607

Priority

  • US 9610494 W 19960607
  • US 48353095 A 19950607

Abstract (en)

[origin: WO9640199A1] The present invention relates, in general, to methods of treating diseases resulting from interactions between immune complexes and Fc receptors. In particular, the present invention relates to methods of modulating the clearance of antibody-coated cells from the circulation by inhibiting phagocytosis and to methods of modulating the interaction of immune complexes with tissue Fc receptors. Further, the invention relates to methods of modulating the activation of immunological processes mediate by Fc receptor activation resulting from antibody-antigen/receptor interaction.

IPC 1-7

C07K 14/705; C12N 15/11; A61K 38/17

IPC 8 full level

C12N 15/09 (2006.01); A61K 31/70 (2006.01); A61K 38/00 (2006.01); A61K 38/17 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 11/00 (2006.01); A61P 29/00 (2006.01); A61P 37/06 (2006.01); C07K 14/735 (2006.01); C12N 5/10 (2006.01); C12N 15/113 (2010.01); C12Q 1/68 (2006.01)

CPC (source: EP)

A61P 11/00 (2018.01); A61P 29/00 (2018.01); A61P 37/06 (2018.01); C07K 14/70535 (2013.01); C12N 15/1137 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C12N 2310/111 (2013.01); C12N 2310/315 (2013.01); C12N 2310/53 (2013.01)

Citation (search report)

  • [XA] WO 9509002 A1 19950406 - UNIV PENNSYLVANIA [US]
  • [A] LAW CHE-LEUNG ET AL: "Molecular cloning of human syk: A B cell protein-tyrosine kinase associated with the surface immunoglobulin M-B cell receptor complex.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 269, no. 16, 1994, pages 12310 - 12319, XP002200453, ISSN: 0021-9258
  • [T] MATSUDA MITSUHIRO ET AL: "Abrogation of the Fc-gamma receptor IIA-mediated phagocytic signal by stem-loop Syk antisense oligonucleotides.", MOLECULAR BIOLOGY OF THE CELL, vol. 7, no. 7, 1996, pages 1095 - 1106, XP008003814, ISSN: 1059-1524

Citation (examination)

  • OLIVER JANET M; BURG DEBRA L; WILSON BRIDGET S; MCLAUGHLIN JERRY L; GEAHLEN ROBERT L: "Inhibition of mast cell Fc-epsilon-R1-mediated signaling and effector function by the Syk-selective inhibitor, piceatannol", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 269, no. 47, 1994, pages 29697 - 29703, ISSN: 0021-9258
  • See also references of WO 9640199A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9640199 A1 19961219; AU 6386996 A 19961230; AU 723595 B2 20000831; CA 2223402 A1 19961219; CA 2223402 C 20120731; EP 0831875 A1 19980401; EP 0831875 A4 20020731; IL 122338 A0 19980405; JP H11507824 A 19990713

DOCDB simple family (application)

US 9610494 W 19960607; AU 6386996 A 19960607; CA 2223402 A 19960607; EP 96923327 A 19960607; IL 12233896 A 19960607; JP 50230197 A 19960607