EP 0969831 A1 20000112 - NASAL MELATONIN COMPOSITION
Title (en)
NASAL MELATONIN COMPOSITION
Title (de)
MELATONINHALTIGE NASENARZNEIMITTEL
Title (fr)
COMPOSITION PERMETTANT L'ADMINISTRATION NASALE DE MELATONINE
Publication
Application
Priority
- EP 98920488 A 19980324
- EP 9801783 W 19980324
- EP 97200920 A 19970326
Abstract (en)
[origin: EP0867181A1] The invention relates to a pharmaceutical composition for nasal administration comprising melatonin and an additive selected from glycerol, cyclodextrin, and mixtures thereof. The pharmaceutical composition comprising an aqueous composition of 0.5 to 10 mg/ml of melatonin, and one or more of 1 to 250 mg/ml of cyclodextrin and 5 to 50% by volume of glycerol, can be used for the preparation of a nasal dosage form comprising daily dosage units of 0.05 to 1 mg of melatonin, and preferably of about 0.1 to 0.8 mg of melatonin, for sleep induction in men.
IPC 1-7
IPC 8 full level
A61K 9/00 (2006.01); A61K 31/40 (2006.01); A61K 31/4045 (2006.01); A61K 47/48 (2006.01)
CPC (source: EP)
A61K 9/0043 (2013.01); A61K 31/4045 (2013.01); A61K 47/6949 (2017.07); A61K 47/6951 (2017.07); B82Y 5/00 (2013.01)
Citation (search report)
See references of WO 9842333A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
EP 0867181 A1 19980930; EP 0969831 A1 20000112; WO 9842333 A1 19981001
DOCDB simple family (application)
EP 97200920 A 19970326; EP 9801783 W 19980324; EP 98920488 A 19980324