EP 1140155 A1 20011010 - IMPROVED RECOMBINANT HEPATITIS B SURFACE ANTIGEN
Title (en)
IMPROVED RECOMBINANT HEPATITIS B SURFACE ANTIGEN
Title (de)
VERBESSERTE REKOMBINANTE HEPATITIS B OBERFLÄCHENANTIGENE
Title (fr)
ANTIGENE D'ENVELOPPE D'HEPATITE B DE RECOMBINAISON AMELIORE
Publication
Application
Priority
- US 9930770 W 19991222
- US 11340098 P 19981223
Abstract (en)
[origin: WO0037104A1] The present invention provides an improved rHBsAg that exhibits a higher antigenicity and immunogenicity than that previously known in the art. A method of making the improved rHBsAg is also provided. The improved HBsAg is used to provide vaccines with lower amounts of active ingredient, vaccines with higher immunogenicity and combination vaccines which produce and protective immunization against infection by hepatitis B virus and other infectious agents.
IPC 1-7
A61K 39/00; A61K 39/29; A61K 39/295; A61K 45/00; C07K 14/00; C12N 15/09
IPC 8 full level
C12N 15/09 (2006.01); A61K 39/05 (2006.01); A61K 39/08 (2006.01); A61K 39/09 (2006.01); A61K 39/095 (2006.01); A61K 39/10 (2006.01); A61K 39/13 (2006.01); A61K 39/25 (2006.01); A61K 39/29 (2006.01); A61K 39/295 (2006.01); A61P 31/12 (2006.01); C07K 14/02 (2006.01); C12P 21/02 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP)
A61K 39/12 (2013.01); A61P 31/12 (2018.01); C07K 14/005 (2013.01); A61K 39/00 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/55505 (2013.01); C12N 2730/10122 (2013.01); C12N 2730/10134 (2013.01); Y02A 50/30 (2018.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0037104 A1 20000629; AU 2212100 A 20000712; CA 2355680 A1 20000629; EP 1140155 A1 20011010; EP 1140155 A4 20041103; JP 2002532116 A 20021002
DOCDB simple family (application)
US 9930770 W 19991222; AU 2212100 A 19991222; CA 2355680 A 19991222; EP 99966613 A 19991222; JP 2000589214 A 19991222