EP 1397485 A2 20040317 - CELL POPULATIONS FOR DETECTING NEURONAL TARGETS AND POTENTIAL ACTIVE INGREDIENTS
Title (en)
CELL POPULATIONS FOR DETECTING NEURONAL TARGETS AND POTENTIAL ACTIVE INGREDIENTS
Title (de)
ZELLPOPULATIONEN ZUR AUFFINDUNG NEURONALER TARGETS UND POTENTIELLER WIRKSTOFFE
Title (fr)
POPULATIONS DE CELLULES DESTINEES A LA DETECTION DE CIBLES NEURONALES ET DE PRINCIPES ACTIFS POTENTIELS
Publication
Application
Priority
- DE 10127008 A 20010605
- DE 10216045 A 20020411
- EP 0205968 W 20020531
Abstract (en)
[origin: WO02099087A2] The invention relates to populations of neuronal cells containing receptors from the group of dopamine receptors, serotonin receptors and adrenergic receptors, and not producing neurotransmitters which bind to said receptors. Said cell populations are suitable for detecting neuronal targets for analysing neuronal diseases, and for detecting potential pharmaceutical active ingredients which especially act against neuronal diseases. The invention also relates to a method for detecting such targets and active ingredients.
IPC 1-7
IPC 8 full level
A61P 25/28 (2006.01); C12N 5/0793 (2010.01)
CPC (source: EP)
A61P 25/28 (2017.12); C12N 5/0619 (2013.01); C12N 2503/02 (2013.01); C12N 2510/00 (2013.01)
Citation (search report)
See references of WO 02099087A2
Citation (examination)
- US 5654189 A 19970805 - LEE VIRGINIA [US], et al
- GUILLEMAIN I. ET AL: "Human NT2 Neurons Express a Large Variety of Neurotransmission Phenotypes In Vitro", THE JOURNAL OF COMPARATIVE NEUROLOGY, vol. 422, no. 3, 3 July 2000 (2000-07-03), pages 380 - 395, XP009043336
- BORLONGAN C.V. ET AL: "Transplantation of Cryopreserved Human Embryonal Carcinoma-Derived Neurons (NT2N Cells) Promotes Functional Recovery in Ischemic Rats", EXPERIMENTAL NEUROLOGY, vol. 149, no. 2, February 1998 (1998-02-01), pages 310 - 321, XP000961826, DOI: doi:10.1006/exnr.1997.6730
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 02099087 A2 20021212; WO 02099087 A3 20030410; EP 1397485 A2 20040317
DOCDB simple family (application)
EP 0205968 W 20020531; EP 02754603 A 20020531