EP 1517903 A2 20050330 - MARKED MALEIMIDE COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR MARKING MACROMOLECULES
Title (en)
MARKED MALEIMIDE COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR MARKING MACROMOLECULES
Title (de)
MARKIERTE MALEIMIDVERBINDUNGEN, VERFAHREN ZU DEREN HERSTELLUNG UND VERWENDUNG ZUR MARKIERUNG VON MAKROMOLEKÜLEN
Title (fr)
COMPOSES DE MALEIMIDES MARQUES, LEUR PROCEDE DE PREPARATION ET LEUR UTILISATION POUR LE MARQUAGE DE MACROMOLECULES
Publication
Application
Priority
- FR 0302028 W 20030630
- FR 0208203 A 20020701
Abstract (en)
[origin: WO2004002984A2] The invention concerns maleimide compounds marked with Fluor 18 of general formula (I), wherein: m represents an integer from 0 to 10; n represents an integer from 1 to 10; Y represents a group selected among optionally substituted heterocyclic, monocyclic or bicyclic groups; X represents a radical of formula (U) a -((CR1R2) b -(V) c) d -((CR3R4) e- (W) f) g-, wherein: a, b, c, d, e, f, g represent each independently an integer from 1 to 10; 0 A 10; U, V and W represent each independently -NR1-, -O-, -S-,formula (II), ethynyl, -CR1=CR2-, -(C=0)-, -(C=S)-, -C=NR1)-, -C(=0) 0-, -(C=S) S-, -C(=NR1)NR2-, -CR1R2-, -CR1OR2-, -CR1NR2R3. The invention also concerns a method for preparing said compounds, their use for marking macromolecules and complexes of said compounds with a macromolecule. The invention further concerns a kit for analysis, detection, or diagnosis using said complexes. The invention finally concerns the use of the complexes in a medical imaging method such as position emission tomography (PET).<>
IPC 1-7
IPC 8 full level
A61K 51/04 (2006.01); A61K 51/08 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01)
CPC (source: EP US)
A61K 51/0455 (2013.01 - EP US); A61K 51/088 (2013.01 - EP US); C07D 401/06 (2013.01 - EP US); C07D 401/12 (2013.01 - EP US)
Citation (search report)
See references of WO 2004002984A2
Citation (examination)
WO 2004003016 A2 20040108 - COMMISSARIAT ENERGIE ATOMIQUE [FR], et al
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
FR 2841554 A1 20040102; FR 2841554 B1 20080118; AU 2003259312 A1 20040119; CA 2491193 A1 20040108; CA 2491193 C 20130416; EP 1517903 A2 20050330; JP 2006504640 A 20060209; US 2005249662 A1 20051110; US 7456202 B2 20081125; WO 2004002984 A2 20040108; WO 2004002984 A3 20040422
DOCDB simple family (application)
FR 0208203 A 20020701; AU 2003259312 A 20030630; CA 2491193 A 20030630; EP 03761670 A 20030630; FR 0302028 W 20030630; JP 2004516901 A 20030630; US 51761204 A 20041222