Global Patent Index - EP 1615614 A4

EP 1615614 A4 20070822 - OPTIMAL POLYVALENT VACCINE FOR CANCER

Title (en)

OPTIMAL POLYVALENT VACCINE FOR CANCER

Title (de)

OPTIMALE POLYVALENTE VAKZINE GEGEN KREBS

Title (fr)

VACCIN POLYVALENT OPTIMAL CONTRE LE CANCER

Publication

EP 1615614 A4 20070822 (EN)

Application

EP 04759415 A 20040409

Priority

  • US 2004011122 W 20040409
  • US 46162203 P 20030409

Abstract (en)

[origin: WO2004091507A2] This invention also provides a method for identification of the optimal combination of a polyvalent vaccine against a cancer comprising steps of: a) selection of an appropriate cancer cell line; and b) detection of the expression of antigens on the surface of said cell line of the cancer, wherein the antigens expressed will be used in the polyvalent vaccine. This invention also provides a method for identification of the optimal combination of a polyvalent vaccine against a cancer comprising steps of: a) selection of an appropriate cancer cell line and b) detection of the immunogenicity will be used in the polyvalent vaccine. This invention provides various uses of the identified polyvalent vaccine.

IPC 8 full level

G01N 33/574 (2006.01); A61K 39/00 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/543 (2006.01); G01N 33/68 (2006.01)

IPC 8 main group level

A61K (2006.01)

CPC (source: EP)

A61P 35/00 (2017.12); G01N 33/5023 (2013.01); G01N 2500/10 (2013.01)

Citation (search report)

  • [X] WO 03003985 A2 20030116 - SLOAN KETTERING INST CANCER [US], et al
  • [X] RAGUPATHI G ET AL: "THE CASE FOR POLYVALENT CANCER VACCINES THAT INDUCE ANTIBODIES", EXPERT REVIEW OF VACCINES, FUTURE DRUGS, LONDON, GB, vol. 1, no. 2, August 2002 (2002-08-01), pages 193 - 206, XP008048224, ISSN: 1476-0584
  • [X] RAGUPATHI G ET AL: "Comparison of antibody titers after immunization with monovalent or tetravalent KLH conjugate vaccines", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 20, no. 7-8, 15 January 2002 (2002-01-15), pages 1030 - 1038, XP004332972, ISSN: 0264-410X
  • [X] PATEL JYOTI D ET AL: "TARGETING LETHAL MINIMAL RESIDUAL DISEASE IN SMALL CELL LUNG CANCER", SEMINARS IN ONCOLOGY, W.B. SAUNDERS,, US, vol. 30, no. 1, February 2003 (2003-02-01), pages 79 - 85, XP008077869, ISSN: 0093-7754
  • [Y] ZHANG SHENGLE ET AL: "Selection of tumor antigens as targets for immune attack using immunohistochemistry: I. Focus on gangliosides", INTERNATIONAL JOURNAL OF CANCER, vol. 73, no. 1, 1997, pages 42 - 49, XP002431043, ISSN: 0020-7136
  • [Y] GILEWSKI T ET AL: "Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: a phase I trial", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 98, no. 6, 13 March 2001 (2001-03-13), pages 3270 - 3275, XP002964246, ISSN: 0027-8424
  • See references of WO 2004091507A2

Citation (examination)

  • LIVINGSTON P.: "Immunization of mice with polysialic acid and N-propionylated polysialic acid-KLH conjugates plus QS-21 results in antibodies against human small cell lung cancer cells", PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH ANNUAL MEETING, vol. 42, March 2001 (2001-03-01), pages 288, XP008012617
  • LIVINGSTON P.: "Current status of cancer vaccines against cell surface antigens on small cell lung cancer.", BIOTECNOLOGIA APLICADA, vol. 19, no. 3-4, 2002, pages 192
  • KRUG L.M. ET AL: "Vaccination of Small Cell Lung Cancer Patients with Polysialic Acid or N-Propionylated Polysialic Acid Conjugated to Keyhole Limpet Hemocyanin", CLINICAL CANCER RESEARCH, vol. 10, no. 3, 1 February 2004 (2004-02-01), pages 916 - 923
  • KRUG ET AL: "Development of a tetravalent small cell lung cancer (SCLC) vaccine containing GM2, fucosyl GM1, Globo H, and polysialic acid", LUNG CANCER, vol. 41, 1 August 2003 (2003-08-01), pages S47, XP005875064
  • KRUG LEE M.: "Vaccine therapy for small cell lung cancer", SEMINARS IN ONCOLOGY, vol. 31, no. 1, 1 February 2004 (2004-02-01), pages 112 - 116, XP008098213

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2004091507 A2 20041028; WO 2004091507 A3 20051215; CA 2521812 A1 20041028; EP 1615614 A2 20060118; EP 1615614 A4 20070822; JP 2006522828 A 20061005

DOCDB simple family (application)

US 2004011122 W 20040409; CA 2521812 A 20040409; EP 04759415 A 20040409; JP 2006509902 A 20040409