EP 1627220 A1 20060222 - ARRANGEMENT AND METHOD FOR THE OPTICAL DETECTION OF CHEMICAL AND BIOCHEMICAL MOLECULES AND/OR PARTICLES CONTAINED IN SAMPLES
Title (en)
ARRANGEMENT AND METHOD FOR THE OPTICAL DETECTION OF CHEMICAL AND BIOCHEMICAL MOLECULES AND/OR PARTICLES CONTAINED IN SAMPLES
Title (de)
ANORDNUNG UND VERFAHREN ZUR OPTISCHEN DETEKTION VON IN PROBEN ENTHALTENEN CHEMISCHEN, BIOCHEMISCHEN MOLEK LEN UND/ODER PARTIK ELN
Title (fr)
AGENCEMENT ET PROCEDE POUR LA DETECTION OPTIQUE DE MOLECULES ET/OU DE PARTICULES CHIMIQUES, BIOCHIMIQUES CONTENUES DANS DES ECHANTILLONS
Publication
Application
Priority
- DE 2004001135 W 20040526
- DE 10324973 A 20030527
Abstract (en)
[origin: WO2004106901A1] The invention relates to an arrangement and a method for the optical detection of chemical and biochemical molecules and/or particles contained in samples, using surface plasmon resonance (SPR) which varies according to the optical refractive index. According to the invention, light from a light source is directed towards an optical detector by means of at least one sensor element which is embodied as an optical waveguide, at least in sections. At least one electroconductive thin layer is provided on the boundary surface of said optical waveguide, beneath a measuring surface. The light guided by the optical waveguide strikes the boundary surface in the region of the thin layer, at angles above the total reflection angle. A front side of the sensor element is provided with an aspherical, convex, optical surface for the light incidence, by which means the light inside the sensor element is focussed in the direction of the boundary surface covered by the at least one thin layer and/or measuring surface, and a second aspherical, convex, optical surface is provided on the front side of the sensor element for the light emergence. The light modified as a result of surface plasmon resonance is directed in a collimated form towards the at least one optical detector by means of said optical surfaces.
IPC 1-7
IPC 8 full level
G01N 21/55 (2006.01); G02B 3/00 (2006.01); G02B 5/30 (2006.01)
CPC (source: EP)
G01N 21/553 (2013.01)
Citation (search report)
See references of WO 2004106901A1
Designated contracting state (EPC)
DE FR GB
DOCDB simple family (publication)
WO 2004106901 A1 20041209; DE 10324973 A1 20041230; DE 10324973 B4 20060413; EP 1627220 A1 20060222
DOCDB simple family (application)
DE 2004001135 W 20040526; DE 10324973 A 20030527; EP 04738589 A 20040526