EP 1960778 A2 20080827 - METHOD FOR DEMONSTRATING PRESENCE OR ABSENCE OF MARKERS ASSOCIATED WITH THE PRESENCE AND/OR THE CHEMOSENSITIVITY OF TUMORS
Title (en)
METHOD FOR DEMONSTRATING PRESENCE OR ABSENCE OF MARKERS ASSOCIATED WITH THE PRESENCE AND/OR THE CHEMOSENSITIVITY OF TUMORS
Title (de)
VERFAHREN ZUR DEMONSTRATION DES VORHANDENSEINS ODER DER ABWESENHEIT VON MIT DEM VORLIEGEN UND/ODER DER CHEMOSENSITIVITÄT VON TUMOREN ASSOZIIERTEN MARKERN
Title (fr)
PROCEDE POUR LA MISE EN EVIDENCE DE LA PRESENCE OU DE L'ABSENCE DE MARQUEURS (EEF1A1 OU MARK3 ) ASSOCIES A LA PRESENCE ET/OU A LA CHIMIOSENSIBILITE DES TUMEURS
Publication
Application
Priority
- EP 2006068943 W 20061127
- FR 0511954 A 20051125
- FR 0511958 A 20051125
Abstract (en)
[origin: WO2007060240A2] The invention concerns a novel diagnostic method for detecting the presence or the absence of a tumor and/or its sensitivity to chemotherapies in a mammal, in particular in a human being, by detecting and/or quantifying the presence of a novel biological marker in a biological sample previously collected in said mammal: an eEF1A1 protein and/or a MARK3 protein. The absence of an eEF1A1 protein or antibodies directed against an eEF1A1 protein or a fragment comprising at least one epitope of said protein, or a low concentration compared to concentrations observed in healthy persons or patients suffering from cancers sensitive to chemotherapies is characteristic of the presence or a tumor a priori resistant to the usual chemotherapies (chemoresistant). The presence of a MARK3 protein or antibodies directed against a MARK3 protein or a fragment comprising at least one epitope of said protein is characteristic of the presence of a tumor.
IPC 8 full level
A61K 31/7105 (2006.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01); C07H 21/02 (2006.01); C07K 14/47 (2006.01); C12N 15/113 (2010.01); C12N 15/12 (2006.01); C12N 15/63 (2006.01); C12P 21/02 (2006.01); G01N 33/50 (2006.01); G01N 33/574 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP US)
A61P 35/00 (2017.12 - EP); C07K 16/30 (2013.01 - EP US); C12N 15/113 (2013.01 - EP US); C12N 15/1137 (2013.01 - EP US); G01N 33/57407 (2013.01 - EP US); C12N 2310/14 (2013.01 - EP US)
Citation (search report)
See references of WO 2007060240A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2007060240 A2 20070531; WO 2007060240 A3 20070907; EP 1960778 A2 20080827; US 2009175871 A1 20090709
DOCDB simple family (application)
EP 2006068943 W 20061127; EP 06841273 A 20061127; US 9488006 A 20061127