Global Patent Index - EP 2013220 A1

EP 2013220 A1 20090114 - METHOD FOR THE PRODUCTION OF BORONIC ACIDS CARRYING CYANOALKYL, CARBOXYL AND AMINOCARBONYL GROUPS AND THEIR DERIVATIVES

Title (en)

METHOD FOR THE PRODUCTION OF BORONIC ACIDS CARRYING CYANOALKYL, CARBOXYL AND AMINOCARBONYL GROUPS AND THEIR DERIVATIVES

Title (de)

VERFAHREN ZUR HERSTELLUNG VON CYANOALKYL-, CARBOXYL- UND AMINOCARBONYLGRUPPEN TRAGENDEN BORONSÄUREN UND IHREN DERIVATEN

Title (fr)

PROCÉDÉ DE PRODUCTION D'ACIDES BORONIQUES PORTANT DES GROUPES CYANOALKYLE, CARBOXYLE ET AMINOCARBONYLE ET LEURS DÉRIVÉS

Publication

EP 2013220 A1 20090114 (DE)

Application

EP 07711737 A 20070301

Priority

  • EP 2007001764 W 20070301
  • DE 102006018524 A 20060421

Abstract (en)

[origin: WO2007121805A1] A process for the manufacture of aminocarbonyl boronic acids of formula (IV) by converting the compounds of formula (III) with a Bronsted base Y(OH)<SUB>n</SUB>in a solvent or a solvent mixture, wherein Z represents an optionally substituted arylene, heteroarylene, alkene, heteroalkene, alkylidene, heteroalkylidene, alkenylidene, heteroalkenylidene, alkynylidene, arylalkylene, heteroarylalkylene, arylheteroalkylene, heteroarylheteroalkylene, alkylheteroarylene, heteroalkylheteroarylene, or alkylarylene group; Y represents a metal or ammonium cation of valence n with 0 < n < 5; and B represents boronic acid, boronic acid ester, or a borate, or a boronic acid anhydride. The aminocarbonyl boronic acids of formula (IV) can be further hydrolyzed to form the carboxy boronic acid of formula (V).

IPC 8 full level

C07F 5/02 (2006.01)

CPC (source: EP US)

C07F 5/025 (2013.01 - EP US)

Citation (search report)

See references of WO 2007121805A1

Designated contracting state (EPC)

DE FR GB IT

Designated extension state (EPC)

AL BA HR MK RS

DOCDB simple family (publication)

WO 2007121805 A1 20071101; EP 2013220 A1 20090114; US 2009286995 A1 20091119

DOCDB simple family (application)

EP 2007001764 W 20070301; EP 07711737 A 20070301; US 29629207 A 20070301