EP 2013220 A1 20090114 - METHOD FOR THE PRODUCTION OF BORONIC ACIDS CARRYING CYANOALKYL, CARBOXYL AND AMINOCARBONYL GROUPS AND THEIR DERIVATIVES
Title (en)
METHOD FOR THE PRODUCTION OF BORONIC ACIDS CARRYING CYANOALKYL, CARBOXYL AND AMINOCARBONYL GROUPS AND THEIR DERIVATIVES
Title (de)
VERFAHREN ZUR HERSTELLUNG VON CYANOALKYL-, CARBOXYL- UND AMINOCARBONYLGRUPPEN TRAGENDEN BORONSÄUREN UND IHREN DERIVATEN
Title (fr)
PROCÉDÉ DE PRODUCTION D'ACIDES BORONIQUES PORTANT DES GROUPES CYANOALKYLE, CARBOXYLE ET AMINOCARBONYLE ET LEURS DÉRIVÉS
Publication
Application
Priority
- EP 2007001764 W 20070301
- DE 102006018524 A 20060421
Abstract (en)
[origin: WO2007121805A1] A process for the manufacture of aminocarbonyl boronic acids of formula (IV) by converting the compounds of formula (III) with a Bronsted base Y(OH)<SUB>n</SUB>in a solvent or a solvent mixture, wherein Z represents an optionally substituted arylene, heteroarylene, alkene, heteroalkene, alkylidene, heteroalkylidene, alkenylidene, heteroalkenylidene, alkynylidene, arylalkylene, heteroarylalkylene, arylheteroalkylene, heteroarylheteroalkylene, alkylheteroarylene, heteroalkylheteroarylene, or alkylarylene group; Y represents a metal or ammonium cation of valence n with 0 < n < 5; and B represents boronic acid, boronic acid ester, or a borate, or a boronic acid anhydride. The aminocarbonyl boronic acids of formula (IV) can be further hydrolyzed to form the carboxy boronic acid of formula (V).
IPC 8 full level
C07F 5/02 (2006.01)
CPC (source: EP US)
C07F 5/025 (2013.01 - EP US)
Citation (search report)
See references of WO 2007121805A1
Designated contracting state (EPC)
DE FR GB IT
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
WO 2007121805 A1 20071101; EP 2013220 A1 20090114; US 2009286995 A1 20091119
DOCDB simple family (application)
EP 2007001764 W 20070301; EP 07711737 A 20070301; US 29629207 A 20070301