EP 2035093 A4 20100217 - METHODS OF TREATING SPINAL CORD INJURY AND MINIMIZING SCARRING
Title (en)
METHODS OF TREATING SPINAL CORD INJURY AND MINIMIZING SCARRING
Title (de)
VERFAHREN ZUR BEHANDLUNG VON RÜCKENMARKSVERLETZUNGEN UND MINIMIERUNG VON NARBENBILDUNG
Title (fr)
PROCÉDÉS POUR TRAITER UNE LÉSION DE LA MOELLE ÉPINIÈRE ET POUR MINIMISER L'ÉTENDUE DE LA CICATRISATION
Publication
Application
Priority
- US 2007013140 W 20070604
- US 81375906 P 20060614
Abstract (en)
[origin: WO2007145889A1] The invention is directed to methods of promoting the healing of spinal cord injury. The invention is further directed to methods of minimizing the extent of scarring following spinal cord injury. Such methods utilize novel compositions, including but not limited to extraembryonic cytokine secreting cells (herein referred to as ECS cells), including, but not limited to, amnion-derived multipotent progenitor cells (herein referred to as AMP cells) and conditioned media derived therefrom (herein referred to as amnion-derived cellular cytokine suspension or ACCS), each alone or in combination with each other and/or other agents.
IPC 8 full level
A61P 25/00 (2006.01); A61K 35/48 (2015.01); A61K 35/50 (2006.01)
CPC (source: EP)
A61K 35/48 (2013.01); A61P 25/00 (2017.12); C12N 5/0605 (2013.01); C12N 2500/90 (2013.01)
Citation (search report)
- [XDI] SANKAR V ET AL: "Role of human amniotic epithelial cell transplantation in spinal cord injury repair research.", NEUROSCIENCE, vol. 118, no. 1, 25 April 2003 (2003-04-25), pages 11 - 17, XP002562017, ISSN: 0306-4522
- [A] UCHIDA S ET AL: "NEUROTROPHIC FUNCTION OF CONDITIONED MEDIUM FROM HUMAN AMNIOTIC EPITHELIAL CELLS", JOURNAL OF NEUROSCIENCE RESEARCH, WILEY-LISS, US, vol. 62, no. 4, 15 November 2000 (2000-11-15), pages 585 - 590, XP001029688, ISSN: 0360-4012
- [XDP] WU ZHI-YUAN ET AL: "Transplantation of human amniotic epithelial cells improves hindlimb function in rats with spinal cord injury.", CHINESE MEDICAL JOURNAL 20 DEC 2006, vol. 119, no. 24, 20 December 2006 (2006-12-20), pages 2101 - 2107, XP002562018, ISSN: 0366-6999
- See references of WO 2007145889A1
Citation (examination)
- WO 2006105152 A2 20061005 - STEMNION LLC [US], et al
- DE CASTRO M ET AL: "Evaluation of human serum albumin as a substitute of foetal bovine serum for cell culture", INTERNATIONAL JOURNAL OF PHARMACEUTICS, ELSEVIER BV, NL, vol. 310, no. 1-2, 9 March 2006 (2006-03-09), pages 8 - 14, XP025113345, ISSN: 0378-5173, [retrieved on 20060309], DOI: 10.1016/J.IJPHARM.2005.10.028
- SAKURAGAWA N ET AL: "EXPRESSION OF MARKERS FOR BOTH NEURONAL AND GLIAL CELLS IN HUMAN AMNIOTIC EPITHELIAL CELLS", NEUROSCIENCE LETTERS, LIMERICK, IE, vol. 209, 1 January 1996 (1996-01-01), pages 9 - 12, XP000983495, ISSN: 0304-3940, DOI: 10.1016/0304-3940(96)12599-4
- NORIO SAKURAGAWA ET AL: "Evidence for active acetylcholine metabolism in human amniotic epithelial cells: applicable to intracerebral allografting for neurologic disease", NEUROSCIENCE LETTERS, vol. 232, no. 1, 1 August 1997 (1997-08-01), pages 53 - 56, XP055062974, ISSN: 0304-3940, DOI: 10.1016/S0304-3940(97)00570-3
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2007145889 A1 20071221; EP 2035093 A1 20090318; EP 2035093 A4 20100217
DOCDB simple family (application)
US 2007013140 W 20070604; EP 07777388 A 20070604