Global Patent Index - EP 2311564 A1

EP 2311564 A1 20110420 - Microfluidic system with chamber and means for generating alternating magnetic fields

Title (en)

Microfluidic system with chamber and means for generating alternating magnetic fields

Title (de)

Mikrofluidisches System mit Kammer und Mitteln zum Erzeugen von sich ändernden Magnetfeldern

Title (fr)

Système microfluidique doté d'une chambre et moyen pour générer des champs magnétiques alternatifs

Publication

EP 2311564 A1 20110420 (EN)

Application

EP 09172166 A 20091005

Priority

EP 09172166 A 20091005

Abstract (en)

Microfluidic system comprising a processing chamber (1) and an assembly (2a-b,2a-d) for generating mutually alternating magnetic fields, provided in the vicinity of the processing chamber. Preferably, the assembly comprises a yoke (3) at one location relative to the processing chamber and at least one yoke (3) at another location relative to the processing chamber, each of the yokes comprising at least two yoke legs (4a,4b), connected to an alternatable magnetic field source between them, as well as an open end area including a small gap area (5) between both open yoke leg ends, the small gap areas of the yokes involved being located at different locations relative to the processing chamber, the alternatable magnetic field sources involved being arranged that, alternately, in one period a magnetic field is generated in the small gap area at one location of the processing chamber, and in another period a magnetic field is generated in the small gap area at another location of the processing chamber. The switchable magnetic field source may include a permanent magnet (6) and a rotatable magnet (7), either made of neodymium.

IPC 8 full level

B01L 3/00 (2006.01)

CPC (source: EP)

B01L 3/50273 (2013.01); B01L 3/502761 (2013.01); B01L 2200/0647 (2013.01); B01L 2200/0668 (2013.01); B01L 2300/0816 (2013.01); B01L 2400/043 (2013.01)

Citation (applicant)

  • US 4230685 A 19801028 - SENYEI ANDREW E, et al
  • US 4554088 A 19851119 - WHITEHEAD ROY A [US], et al
  • US 4628037 A 19861209 - CHAGNON MARK S [US], et al
  • B., HAUKANES; C. KVAM: "Application of Magnetic Beads in Bioassays", BIO/TECHNOLOGY, vol. 11, 1993, pages 60 - 63
  • J. G. TRELEAVEN: "Removal of Neuroblastoma Cells from Bone Marrow with Monoclonal Antibodies Conjugated to Magnetic Microspheres", LANCET, 14 January 1984 (1984-01-14), pages 70 - 73
  • F. VARTDAL: "Depletion of T Lymphocytes from Human Bone Marrow", TRANSPLANTATION, vol. 43, 1987, pages 366 - 71
  • T. LEA: "Magnetic Monosized Polymer Particles for Fast and Specific Fractionation of Human Mononuclear Cells", SCANDINAVIAN JOURNAL OF IMMUNOLOGY, vol. 22, 1985, pages 207 - 16
  • "Advances in Biomagnetic Separations", 1994, EATON PUBLISHING CO.

Citation (search report)

  • [XI] US 2008160634 A1 20080703 - SU XING [US], et al
  • [X] WO 2004078316 A1 20040916 - ECOLE POLYTECH [CH], et al
  • [XA] DE 10355460 A1 20050630 - UNIV BERLIN HUMBOLDT [DE]
  • [X] SMISTRUP K ET AL: "Microelectromagnet for magnetic manipulation in lab-on-a-chip systems", JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 300, no. 2, 1 May 2006 (2006-05-01), pages 418 - 426, XP024984333, ISSN: 0304-8853, [retrieved on 20060501]

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

Designated extension state (EPC)

AL BA RS

DOCDB simple family (publication)

EP 2311564 A1 20110420

DOCDB simple family (application)

EP 09172166 A 20091005