EP 2363877 A1 20110907 - Method for chemical analysis
Title (en)
Method for chemical analysis
Title (de)
Verfahren zur chemischen Analyse
Title (fr)
Procédé pour l'analyse chimique
Publication
Application
Priority
CH 2712010 A 20100302
Abstract (en)
In a method for chemical analysis a first group of particles of a sample of interest is ionized using a first ionization method for generating a first group of ions. A second group of particles of the sample of interest is ionized using a second ionization method which is different from the first ionization method for generating a second group of ions. The first group of ions and the second group of ions are analyzed in a mass analyzer (120), whereas ions of the first group and ions of the second group are detected using the same detector (124) of the mass analyzer. At least one of the ionization methods is operated in a pulsed manner and/or the ionized particles of at least one of the groups are transmitted to the mass analyzer in a pulsed manner. At least in a time interval the first ionization method and the second ionization method are operated simultaneously and ions of the first group and ions of the second group are both transmitted to the mass analyzer (120). This method and a corresponding apparatus have an improved capability to identify chemical compounds. In particular, the improvement may be achieved by high-speed multiplexing of the different ionization methods.
IPC 8 full level
H01J 49/10 (2006.01)
CPC (source: EP)
H01J 49/107 (2013.01); H01J 49/24 (2013.01); H01J 49/40 (2013.01)
Citation (applicant)
- US 6469297 B1 20021022 - KATO YOSHIAKI [JP]
- US 7294830 B2 20071113 - HIEFTJE GARY M [US], et al
Citation (search report)
- [XI] WO 2008037073 A1 20080403 - MDS ANALYTICAL TECH BU MDS INC [CA], et al
- [XI] US 2005247871 A1 20051110 - BRYDEN WAYNE A [US], et al
- [XI] US 2006091308 A1 20060504 - BOYLE JAMES G [US], et al
- [XI] WO 2005031306 A2 20050407 - SYAGEN TECHNOLOGY [US], et al
Citation (examination)
- EP 2112679 A2 20091028 - SHIMADZU CORP [JP]
- JP 2008249694 A 20081016 - HITACHI HIGH TECH CORP
- BUCKNALL M ET AL: "Practical quantitative biomedical applications of MALDI-TOF mass spectrometry", JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROME, ELSEVIER SCIENCE INC, US, vol. 13, no. 9, 1 September 2002 (2002-09-01), pages 1015 - 1027, XP004381302, ISSN: 1044-0305, DOI: 10.1016/S1044-0305(02)00426-9
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
Designated extension state (EPC)
AL BA ME RS
DOCDB simple family (publication)
DOCDB simple family (application)
EP 10405080 A 20100419