EP 2430427 A1 20120321 - METHOD AND DEVICE FOR DETECTING TUMOROUS LIVING CELL TISSUE
Title (en)
METHOD AND DEVICE FOR DETECTING TUMOROUS LIVING CELL TISSUE
Title (de)
VERFAHREN UND VORRICHTUNG ZUR ERKENNUNG VON TUMORBEHAFTETEM LEBENDEM ZELLGEWEBE
Title (fr)
PROCÉDÉ ET DISPOSITIF DE DÉTECTION DE TISSUS CELLULAIRES VIVANTS ATTEINTS D'UNE TUMEUR
Publication
Application
Priority
- DE 2010000559 W 20100512
- EP 09006583 A 20090515
- DE 102009031775 A 20090701
- EP 10730694 A 20100512
Abstract (en)
[origin: WO2010130254A1] The invention relates to a method and a device for detecting tumorous living cell tissue. It also relates to a method and a device for detecting tumorous cell tissue in collected samples of living cell tissue. In the method, a radiation source is used to emit electromagnetic radiation in a locally defined manner onto cell tissue and, after the radiation source has been switched off, the decay behaviour of the inherent fluorescence intensity excited in the cell tissue by the electromagnetic radiation is detected on the cell tissue by a detector, with temporal and spectral resolution and with a known scanning rate or known scanning rates for at least one wavelength. With the measured intensity values that are obtained, the difference autocorrelation function C(t) of the intensity decay behaviour is determined, from which the fractal dimension DF for the respective irradiated cell tissue is calculated, and the value of the fractal dimension DF is used for a classification in respect of a tumorous invasion of the respective irradiated cell tissue.
IPC 8 full level
G01N 21/64 (2006.01); A61B 5/00 (2006.01)
CPC (source: EP KR US)
A61B 5/0059 (2013.01 - EP KR US); A61B 5/0071 (2013.01 - KR); G01N 21/6408 (2013.01 - EP KR US); G01N 21/6486 (2013.01 - EP KR US)
Citation (search report)
See references of WO 2010130254A1
Citation (examination)
- GERICH C E ET AL: "Detection of cancer cells in prostate tissue with time-resolved fluorescence spectroscopy", OPTICAL INTERACTIONS WITH TISSUE AND CELLS XXII, SPIE, 1000 20TH ST. BELLINGHAM WA 98225-6705 USA, vol. 7897, no. 1, 10 February 2011 (2011-02-10), pages 1 - 12, XP060007307, DOI: 10.1117/12.876094
- JAN KLATT ET AL: "Fractal dimension of time-resolved autofluorescence discriminates tumour from healthy tissues in the oral cavity", JOURNAL OF CRANIO-MAXILLO-FACIAL SURGERY, vol. 42, no. 6, 1 September 2014 (2014-09-01), GB, pages 852 - 854, XP055329228, ISSN: 1010-5182, DOI: 10.1016/j.jcms.2013.12.004
- ANONYMOUS: "Web-OPAC V3.0.0.8477", 1 January 2013 (2013-01-01), XP055336933, Retrieved from the Internet <URL:http://bond.azw.ac.at/webopac/index.asp?detmediennr=2> [retrieved on 20170119]
- GERICH CE: "Diplom-Arbeit: Untersuchung zum nicht-exponentiellen Abklingverhalten von Laser induzierter Auto-Fluoreszenz zur Diagnose von Prostata-Carcinom", 2008, EDUARD WALLNÖFER ZENTRUM 1: UMIT PRIVATE UNIVERSITÄT FÜR GESUNDHEITSWISSENSCHAFTEN
- GERICH CE, OPITZ J, SCHREIBER J: "Machbarkeits-Studie Zeitaufgelöste Fluoreszenz zur Krebsdiagnose. Fraunhofer Institut für zerstörungsfreie Prüfverfahren", 30 September 2008, FRAUNHOFER INSTITUT FÜR ZERSTÖRUNGSFREIE PRÜFVERFAHREN, Dresden
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
DOCDB simple family (publication)
WO 2010130254 A1 20101118; EP 2430427 A1 20120321; KR 101746010 B1 20170612; KR 20120036855 A 20120418; US 2012252057 A1 20121004; US 8981317 B2 20150317
DOCDB simple family (application)
DE 2010000559 W 20100512; EP 10730694 A 20100512; KR 20117030090 A 20100512; US 201013320610 A 20100512