EP 2601176 A1 20130612 - NOVEL SALTS OF SAXAGRLIPTIN WITH ORGANIC DI-ACIDS
Title (en)
NOVEL SALTS OF SAXAGRLIPTIN WITH ORGANIC DI-ACIDS
Title (de)
NEUARTIGE SALZE AUS SAXAGLIPTIN MIT ORGANISCHEN DI-SÄUREN
Title (fr)
NOUVEAUX SELS DE SAXAGLIPTINE COMPORTANT DES DIACIDES ORGANIQUES
Publication
Application
Priority
- EP 10172108 A 20100806
- EP 2011063423 W 20110804
- EP 11741455 A 20110804
Abstract (en)
[origin: WO2012017029A1] The present invention refers to a crystalline compound comprising a mixture of a compound of formula (I) (INN:Saxagliptin) and an organic C-4diacid of formula (II), wherein R represents H or OH and X and Y represent either both H or form a bond with each other, the resulting double bond being in Z-configuration, with the proviso that R represents H if X and Y represent a bond, or a hydrate thereof, wherein the molar ratio of the compound of formula (I) to the organic C4-di-acid of formula (II) is of from 1:0.8 to 1:1.2, as well as a process for obtaining the same.
IPC 8 full level
C07D 209/52 (2006.01); A61K 31/403 (2006.01); A61P 3/00 (2006.01)
CPC (source: EP)
A61P 3/00 (2017.12); C07D 209/52 (2013.01)
Citation (search report)
See references of WO 2012017029A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
DOCDB simple family (application)
EP 2011063423 W 20110804; EP 11741455 A 20110804