EP 3245285 A1 20171122 - COMBINATION OF BACTERIAL CHAPERONES POSITIVELY AFFECTING THE PHYSIOLOGY OF A NATIVE OR ENGINEERED EUKARYOTIC CELL
Title (en)
COMBINATION OF BACTERIAL CHAPERONES POSITIVELY AFFECTING THE PHYSIOLOGY OF A NATIVE OR ENGINEERED EUKARYOTIC CELL
Title (de)
KOMBINATION VON BAKTERIELLEN CHAPERONEN ZUR POSITIV AUSWIRKUNG AUF DIE PHYSIOLOGIE EINER NATIVEN ODER MANIPULIERTEN EUKARYOTISCHEN ZELLE
Title (fr)
COMBINAISON DE CHAPERONNES BACTERIENNES AFFECTANT POSITIVEMENT LA PHYSIOLOGIE D'UNE CELLULE EUCARYOTE NATIVE OU PORTANT UNE INGENIERIE
Publication
Application
Priority
- EP 15305048 A 20150116
- EP 15305049 A 20150116
- EP 2016050832 W 20160115
Abstract (en)
[origin: WO2016113418A1] The invention relates to the expression of a specific combination of three bacterial chaperones in a eukaryotic cell, which significantly improves the growth properties thereof and the properties thereof relating to resistance to physicochemical stresses, especially when said cell comprises additional engineering using at least one non-native gene. A preferred combination of chaperones comprises the chaperones GroES and GroEL of E. coli and the chaperone RbcX of Synechococcus elongatus.
IPC 8 full level
C12N 1/19 (2006.01); C07K 14/195 (2006.01); C07K 14/245 (2006.01); C12N 15/81 (2006.01); C12P 21/00 (2006.01); C12P 21/02 (2006.01)
CPC (source: CN EP KR US)
C07K 14/195 (2013.01 - CN EP KR US); C07K 14/245 (2013.01 - CN EP KR US); C07K 14/395 (2013.01 - US); C12N 15/81 (2013.01 - CN EP KR US); C12P 21/00 (2013.01 - CN EP KR US); C12P 21/02 (2013.01 - CN EP KR US)
Citation (search report)
See references of WO 2016113418A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2016113418 A1 20160721; AU 2016207978 A1 20170713; BR 112017015201 A2 20180313; CA 2973912 A1 20160721; CN 107257851 A 20171017; EP 3245285 A1 20171122; JP 2018501810 A 20180125; KR 20170105079 A 20170918; US 2018187204 A1 20180705
DOCDB simple family (application)
EP 2016050832 W 20160115; AU 2016207978 A 20160115; BR 112017015201 A 20160115; CA 2973912 A 20160115; CN 201680005924 A 20160115; EP 16700765 A 20160115; JP 2017537495 A 20160115; KR 20177022784 A 20160115; US 201615542682 A 20160115