Global Patent Index - EP 3994283 A4

EP 3994283 A4 20221012 - METHOD OF TESTING FOR SPECIFIC ORGANISMS IN AN INDIVIDUAL

Title (en)

METHOD OF TESTING FOR SPECIFIC ORGANISMS IN AN INDIVIDUAL

Title (de)

TESTVERFAHREN FÜR SPEZIFISCHE ORGANISMEN BEI EINER PERSON

Title (fr)

PROCÉDÉ DE RECHERCHE D'ORGANISMES SPÉCIFIQUES CHEZ UN INDIVIDU

Publication

EP 3994283 A4 20221012 (EN)

Application

EP 20849772 A 20200731

Priority

  • US 201962882367 P 20190802
  • US 201962892409 P 20190827
  • US 202062991190 P 20200318
  • US 202063002486 P 20200331
  • US 2020044605 W 20200731

Abstract (en)

[origin: WO2021026025A2] A method of testing for specific organisms in an individual comprising the steps of: a) screening the individual; b) acquiring a stool sample from the individual; c) processing the stool sample to obtain the individual's microbiome; d) sequencing the microbiome of the individual; and e) analyzing the microbiome of the individual to determine whether one or more specific organisms are present in the individual, whereby a health condition of the individual is determined. The step of processing can comprise the sub-steps of: i) extracting DNA from the stool sample, which comprises adding the stool sample to a bead beating tube, achieving cell lysis, capturing the DNA on a silica membrane in a spin-column, and washing and eluting the DNA from the membrane; and ii) purifying the extracted DNA. A method of determining whether an individual has a health condition comprising the same steps. A stool sample collection kit.

IPC 8 full level

C12Q 1/689 (2018.01); C12Q 1/6883 (2018.01); C12Q 1/70 (2006.01); G01N 33/574 (2006.01); G16B 30/00 (2019.01)

CPC (source: EP)

C12Q 1/6883 (2013.01); C12Q 1/689 (2013.01); C12Q 1/70 (2013.01); Y02A 50/30 (2017.12)

Citation (search report)

  • [X] WO 2018085817 A1 20180511 - ZYMO RES CORPORATION [US]
  • [XYI] WO 2016164402 A1 20161013 - OKLAHOMA MED RES FOUND [US]
  • [X] WO 2014138999 A1 20140918 - UNIV OTTAWA [CA]
  • [XYI] SOURAV SEN GUPTA ET AL: "Metagenome of the gut of a malnourished child", GUT PATHOGENS, BIOMED CENTRAL LTD, LONDON, UK, vol. 3, no. 1, 20 May 2011 (2011-05-20), pages 7, XP021102178, ISSN: 1757-4749, DOI: 10.1186/1757-4749-3-7
  • [X] KNOLL REBECCA L. ET AL: "Gut microbiota differs between children with Inflammatory Bowel Disease and healthy siblings in taxonomic and functional composition: a metagenomic analysis", AMERICAN JOURNAL OF PHYSIOLOGY - GASTROINTESTINAL AND LIVER PHYSIOLOGY, vol. 312, no. 4, 1 April 2017 (2017-04-01), US, pages G327 - G339, XP055957978, ISSN: 0193-1857, DOI: 10.1152/ajpgi.00293.2016
  • [X] PASCAL VICTORIA ET AL: "A microbial signature for Crohn's disease", GUT MICROBIOTA, vol. 66, no. 5, 1 May 2017 (2017-05-01), UK, pages 813 - 822, XP055958121, ISSN: 0017-5749, Retrieved from the Internet <URL:https://gut.bmj.com/content/gutjnl/66/5/813.full.pdf> DOI: 10.1136/gutjnl-2016-313235
  • [IY] HOGUE STEPHANIE R ET AL: "A Customized At-Home Stool Collection Protocol for Use in Microbiome Studies Conducted in Cancer Patient Populations", MICROBIAL ECOLOGY, SPRINGER US, NEW YORK, vol. 78, no. 4, 30 March 2019 (2019-03-30), pages 1030 - 1034, XP036935475, ISSN: 0095-3628, [retrieved on 20190330], DOI: 10.1007/S00248-019-01346-2
  • [Y] LI NING ET AL: "Correlation of Gut Microbiome Between ASD Children and Mothers and Potential Biomarkers for Risk Assessment", GENOMICS PROTEOMICS AND BIOINFORMATICS, vol. 17, no. 1, 23 April 2019 (2019-04-23), CN, pages 26 - 38, XP055803780, ISSN: 1672-0229, Retrieved from the Internet <URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520911/pdf/main.pdf> DOI: 10.1016/j.gpb.2019.01.002
  • [Y] DUYTSCHAEVER GWEN ET AL: "Cross-Sectional and Longitudinal Comparisons of the Predominant Fecal Microbiota Compositions of a Group of Pediatric Patients with Cystic Fibrosis and Their Healthy Siblings", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 77, no. 22, 15 November 2011 (2011-11-15), US, pages 8015 - 8024, XP055803783, ISSN: 0099-2240, Retrieved from the Internet <URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208981/pdf/zam8015.pdf> DOI: 10.1128/AEM.05933-11
  • See references of WO 2021026025A2

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

DOCDB simple family (publication)

WO 2021026025 A2 20210211; WO 2021026025 A3 20210318; AU 2020326600 A1 20220224; CA 3149221 A1 20210211; EP 3994283 A2 20220511; EP 3994283 A4 20221012

DOCDB simple family (application)

US 2020044605 W 20200731; AU 2020326600 A 20200731; CA 3149221 A 20200731; EP 20849772 A 20200731